HOME > mice > 129+Ter/Sv-Pros1 K196E NCVC mice
Strain Detail: 129+Ter/Sv-Pros1 K196E NCVC
Strain information |
Resource No. |
nbio280 |
Strain name |
129+Ter/Sv-Pros1 K196E NCVC |
Strain Nomenclature |
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Common name/Synonyms |
PS-K196E knockin(129) |
Strain types |
congenic |
Background strain |
129+Ter/Sv Jcl |
Institution |
Department of Molecular Pathogenesis, National Cerebral and Cardiovascular Center Research Institute |
Developer |
Toshiyuki Miyata |
Depositor |
Toshiyuki Miyata (Contact person: Koichi Kokame) |
Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. : contact us |
Animal Health Report |
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Strain description |
The PS-K196E knockin (129) mice are knock-in mice carrying c.586A>G (p.K196E) mutation
introduced in Pros1 locus of 129+Ter/Sv mice by knock-in technology.
Pros1 gene encodes a blood coagulation control factor, protein S.
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References |
- Banno F, Kita T, Fernández JA, Yanamoto H, Tashima Y, Kokame K, Griffin JH, Miyata T.
Exacerbated venous thromboembolism in mice carrying a protein S K196E mutation.
Blood. 2015, 126(19):2247-53.
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Resource information |
Cryopreserved sperm |
In-house |
Genotype |
Pros1 E/E homozygous |
Medium |
FERTIUP |
From other institutions |
Genotype |
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Medium |
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Cryopreserved embryo |
In-house |
Mating System |
Natural mating - perfusion |
Genotype |
Mix of Pros1 E/E homozygous and heterozygous |
Medium |
EFS40 |
From other institutions |
Mating System |
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Genotype |
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Medium |
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Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
Cryopreserved embryo |
Within 1 month |
Live mouse |
Please contact us |
Gene information |
Mutation types |
knockin |
Gene symbol |
Pros1 |
Gene name |
protein S (α) |
Genotyping information |
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