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List of available mice: Mus musculus
Upon receipt of request forms for mouse strain(s), mice will be produced by thawing frozen embryos, followed by embryo transfers. The mice will be sent in two months after the receipt of the request.
We can provide frozen embryos, too.
○Ordering information for the supply of mice○
As of $Date:: 2024-03-18 17:39:03 +0900#$
Resource No. | Strain name | Strain Types | Mutation Types | Genes | Phenotypes | Remarks |
---|---|---|---|---|---|---|
nbio001 | DDY | inbred | Standard strain | Inbred from Yok:ddY | ||
nbio002 | EL | inbred | spontaneous mutation | Epilepsy | Spontaneous mutant | |
nbio003 | HR | inbred | spontaneous mutation | Hr | Alopecia | Spontaneous mutant |
nbio004 | ICGN | inbred | spontaneous mutation | Tenc1 (Tensin 2) | Nephrosis | Mutant from Yok:ICR, mutation in tensin2 gene. |
nbio005 | MPS | inbred | spontaneous mutation | Susceptible to Mycoplasma pneumoniae infection | Mutant from Yok:ICR | |
nbio006 | YPC | inbred | spontaneous mutation | Sgk3/Sgkl/CISK | Poor coat, curly coat, swelling of lymph nodes | Spontaneous mutants, mutation in Sgk3/Sgkl/CISK gene. |
nbio007 | Yok:ddY | outbred | Standard strain | General purpose strain, good breeder | ||
nbio008 | Yok:ICR | outbred | Standard strain | General purpose strain, good breeder | ||
nbio009 | 4C30 | mutant | transgenic | St3gal2 (Siat5, St3GalII) | Dilated cardiomyopathy | Overexpression of β-galactoside α-2,3-sialyltransferase2 transgene |
nbio010 | CD40L | mutant | transgenic | Cd40lg | Systemic Lupus Erythematosus (SLE) | Ectopic expression of CD40 ligands on B cells |
nbio011 | CG | mutant | transgenic | Glb1 | GM1-gangliosidosis | Overexpression of human normal β-galactosidase |
nbio012 | GalA | mutant | transgenic | Glb1 | GM1-gangliosidosis | Overexpression of human mutant β-galactosidase (I51T) |
nbio013 | GalB | mutant | transgenic | Glb1 | GM1-gangliosidosis | Overexpression of human mutant β-galactosidase (R201C) |
nbio014 | GalF | mutant | transgenic | Glb1 | GM1-gangliosidosis | Overexpression of human mutant β-galactosidase (W273L) |
nbio015 | GM1sy | mutant | transgenic | B3galt4 | GM1-gangliosidosis | Overexpression of mouse GM1/GA1 synthase (β1,3-Galactosyltransferase) |
nbio016 | BKO | mutant | knockout | Glb1 | GM1-gangliosidosis | Acid β-galactosidase knockout |
nbio017 | AK | mutant | transgenic+knockout | Glb1 | GM1-gangliosidosis | Overexpression of human mutant β-galactosidase (I51T) without mouse endogenous β-galactosidase |
nbio018 | BK | mutant | transgenic+knockout | Glb1 | GM1-gangliosidosis | Overexpression of human mutant β-galactosidase (R201C) without mouse endogenous β-galactosidase |
nbio019 | CK | mutant | transgenic+knockout | Glb1 | GM1-gangliosidosis | Overexpression of human normal β-galactosidase without mouse endogenous β-galactosidase |
nbio020 | GFP | mutant | transgenic | Gfp (EGFP) | Standard strain | C57BL/6-Tg(CAG-EGFP)C14-Y01-FM131Osb mice, GFP expression in whole body. |
nbio021 | loxP-Rap1GAPII-Tg | mutant | transgenic | Garnl4 (Rap1Gap2) | G protein signaling pathway | Overexpression of FLAG-Tagged human Rap1GAPII |
nbio022 | oma | congenic | spontaneous mutation | Dll3 | Skeletal anomaly | C57BL/6-Dll3oma, mutation of Dll3. Remarkable deformity and fusion of vertebrae, deformity and bifurcation of ribs. |
nbio023 | FOXO1 TG | mutant | transgenic | Foxo1 | Disuse atrophy, loss of skeletal muscle mass | Muscle-specific overexpression of FOXO1 |
nbio025 | Lck-Cre | mutant | transgenic | Lck, Cre | T cell-specific conditional gene disruption | T cell-specific expression of Cre recombinase by Lck proximal promoter |
nbio026 | FAT-UCP2/X | mutant | transgenic | Ucp2 | Obesity, diabetes | Fat-specific overexpression of human UCP2 |
nbio034 | GLUT4-2K | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene containing 2,000 bp of 5'-upstream region |
nbio035 | GLUT4-423/A | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene containing 423 bp of 5'-upstream region (2 lines, A or B) |
nbio036 | GLUT4-423/B | |||||
nbio037 | GLUT4-442/C | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene containing 442 bp of 5'-upstream region (2 lines, C or E) |
nbio038 | GLUT4-442/E | |||||
nbio043 | GLUT4-MEF2/B | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene containing 3,000 bp of 5'-upstream region (2 lines, B or D) |
nbio044 | GLUT4-MEF2/D | |||||
nbio047 | FAT-CDO | mutant | transgenic | Cdo | Diabetes, metabolic syndrome | Fat-specific overexpression of rat cysteine dioxygenase (CDO) by aP2 promoter |
nbio054 | RP58 KO | mutant | knockout | Rp58 | Brain anomaly | RP58 knockout. Lethality shortly after birth. Abnormal layer formation of cerebral cortex. |
nbio055 | Translin KO | mutant | knockout | Tsn (Translin) | Bone marrow failure, Splenomegaly | Translin knockout |
nbio056 | ATF4 KO | mutant | knockout | Atf4 (C/ATF, CREB2, TAXREB67) | Microphthalmia | ATF4 (activating transcription factor-4) knockout |
nbio057 | SOCS1 KO (BALB/c congenic) | congenic | knockout | Socs1 | Immune abnormality | Knockout of SOCS1 (suppressor of cytokine signaling), a signal transduction inhibitor, on the BALB/c background. |
nbio058 | SOCS1 KO (C57BL/6J congenic) | congenic | knockout | Socs1 | Immune abnormality | Knockout of SOCS1 (suppressor of cytokine signaling), a signal transduction inhibitor, on the C57BL/6J background. |
nbio059 | MEF2A | mutant | transgenic | Mef2a | Diabetes | Muscle-specific overexpression of MEF2A |
nbio060 | TAK1flox | mutant | conditional KO | Tak1, Map3k7 | Immune abnormality | Two loxP sites flanking exon 2 of Map3k7 encoding TAK1 |
nbio061 | ADAMTS13 KO | mutant | knockout | Adamts13 | Thrombotic thrombocytopenic purpura (TTP) | Knockout of ADAMTS13, a plasma metalloproteinase. |
nbio074 | ADAMTS13 KO (C57BL/6Cr congenic) | congenic | knockout | Adamts13 | Thrombotic thrombocytopenic purpura (TTP) | Congenic mice derived from ADAMTS13 KO (nbio061) on a C57BL/6Cr background |
nbio062 | NDRG1 KO | mutant | knockout | Ndrg1 | Charcot-Marie-Tooth disease type 4D | Knockout of NDRG1, an ER stress responsive gene. |
nbio063 | NDRG1flox | mutant | conditional KO | Ndrg1 | Charcot-Marie-Tooth disease type 4D | Three loxP sites flanking exon 1 of NDRG1 gene and neomycin resistant gene cassette. |
nbio064 | Cmah Tg VH-G | mutant | transgenic | Cmah | Immunodepression | Lymphocyte-specific expression of Cmah (CMP-Neu5Ac hydroxylase). 3 lines, G (highly expressed line), H or JA (moderate expressed lines). |
nbio065 | Cmah Tg VH-H | |||||
nbio066 | Cmah Tg VH-JA | |||||
nbio067 | Ubc13flox | mutant | conditional KO | Ubc13 | Immune abnormality | Two loxP sites flanking exon 2, 3 and 4 of Ubc13 gene |
nbio069 | YPC-B6 | congenic | spontaneous mutation | Sgk3/Sgkl/CISK | Poor coat, curly coat | Congenic mice derived from YPC (nbio006) on a C57BL/6 background |
nbio070 | SLW | congenic | spontaneous mutation | Npr2 | Chondrodysplasia, Gastrointestinal tract abnormality | Mutant of Npr2, C-type natriuretic peptide (CNP) receptor. |
nbio071 | SIK2-KO | mutant | knockout | Sik2 | Obesity, diabetes | SIK2 knockout |
nbio072 | SOCS-5 Tg/line5-1 | mutant | transgenic | Socs5 | Immune abnormality | Systemic expression of SOCS-5 |
nbio073 | SOCS-5 Tg/line8-1 | |||||
nbio075 | LKB1-DN/B | mutant | transgenic | Stk11 (Lkb1) | Metabolic syndrome | LKB1-DN mice are transgenic mouse lines with skeletal-muscle-specific overexpression of a dominant negative form of LKB1. |
nbio076 | LKB1-DN/C | |||||
nbio077 | GLUT4-ERE1/D | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 3,000 bp of 5'-upstream region with point mutation between 542 and 546 bp. |
nbio078 | GLUT4-ERE2,3/A | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 3,000 bp of 5'-upstream region with point mutation between 513 and 517 bp. |
nbio079 | GLUT4-NF1/A | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 3,000 bp of 5'-upstream region with point mutation on the NF1 site (4 lines). |
nbio080 | GLUT4-NF1/B | |||||
nbio081 | GLUT4-NF1/D-L | |||||
nbio082 | GLUT4-NF1/D-H | |||||
nbio083 | AMPK-DN/A | mutant | transgenic | Ampk | Obesity, Diabetes | Muscle-specific overexpression of rat dominant negative AMPK (6 lines) |
nbio084 | AMPK-DN/B | |||||
nbio085 | AMPK-DN/C | |||||
nbio086 | AMPK-DN/D | |||||
nbio087 | AMPK-DN/E#1 | |||||
nbio088 | AMPK-DN/E#4 | |||||
nbio089 | AMPK-CA/B | mutant | transgenic | Ampk | Obesity, Diabetes | Muscle-specific overexpression of rat constitutive active AMPK (4 lines) |
nbio090 | AMPK-CA/C | |||||
nbio091 | AMPK-CA/D | |||||
nbio092 | AMPK-CA/F | |||||
nbio093 | KLF15/A | mutant | transgenic | Klf15 | Lifestyle diseases, Diabetes | Muscle-specific overexpression of mouse KLF15 (2 lines) |
nbio094 | KLF15/B | |||||
nbio095 | PGC-1α/B | mutant | transgenic | Ppargc1a (PGC-1α) | Luft's disease (mitochondrial myopathy) | Muscle-specific overexpression of mouse PGC-1α (3 lines) |
nbio096 | PGC-1α/D | |||||
nbio097 | PGC-1α/E | |||||
nbio098 | GLUT4-1K/A | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 1,000 bp of 5'-upstream region. |
nbio099 | GLUT4-506/C | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 506 bp of 5'-upstream region (2 lines). |
nbio100 | GLUT4-506/D | |||||
nbio101 | GLUT4-550/B | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 550 bp of 5'-upstream region (2 lines). |
nbio102 | GLUT4-550/C | |||||
nbio103 | GLUT4-582/B | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 582 bp of 5'-upstream region. |
nbio104 | GLUT4-700/A | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 700 bp of 5'-upstream region. |
nbio105 | GLUT4-Mut582/A | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 582 bp of 5'-upstream region with point mutation (3 lines). |
nbio106 | GLUT4-Mut582/B | |||||
nbio107 | GLUT4-Mut582/C | |||||
nbio108 | GLUT4-Mut701 | mutant | transgenic | Glut4 | Diabetes | Expression of mouse GLUT4 gene, containing a part of CAT gene inserted into the 3' region and 701 bp of 5'-upstream region with point mutation. |
nbio109 | Liver-UCP2/A | mutant | transgenic | Ucp2 | Diabetes | Liver-specific overexpression of human UCP2 |
nbio110 | Liver-UCP2/D | |||||
nbio111 | MUSCLE-UCP3 | mutant | transgenic | Ucp3 | Diabetes | Muscle-specific overexpression of human UCP3 |
nbio112 | C3G KO | mutant | knockout | Rapgef1 (C3G, Grf2) | Abnormal embryogenesis | C3G knockout |
nbio113 | hC3G Tg | mutant | transgenic | Rapgef1 (C3G, Grf2) | Abnormal embryogenesis | Systemic overexpression of human C3G by CAG promoter. |
nbio114 | Meg1 Tg/T10L | mutant | transgenic | Meg1 (Grb10) | Type 2 diabetes mellitus | Overexpression of mouse Meg1/Grb10 |
nbio115 | Meg1 Tg/T18L | |||||
nbio116 | Meg1 Tg/T20L | |||||
nbio117 | Meg1 Tg/T27L | |||||
nbio127 | Col11a2-LacZflox-Smad7 | mutant | conditional transgenic | Smad7 | Osteogenesis and Chondrogenesis | Chondrocyte-specific expression of Smad7 by the Cre/loxP system |
nbio128 | 11Prom-Cre | mutant | transgenic | Col11a2, Cre | Differentiation of chondrocyte | Chondrocyte-specific expression of Cre recombinase after the late stage of proliferative chondrocytes |
nbio129 | 11Enh-Cre | mutant | transgenic | Col11a2, Cre | Differentiation of chondrocyte | Chondrocyte-specific expression of Cre recombinase |
nbio130 | Col11a2-Smad6 | mutant | transgenic | Smad6 | Dwarfism, Osteopenia | Chondrocyte-specific expression of Smad6 |
nbio131 | NOD.CD72b | congenic | spontaneous mutation | Cd72 | Diabetes | NOD congenic mice carrying CD72b instead of CD72c |
nbio132 | VE-cadherin-Cre | mutant | transgenic | Cdh5 (VE-cadherin, 7B4/cadherin-5, CD144, VE-Cad, VEC), Cre | Angiogenesis | Vascular endothelial cell-specific expression of Cre recombinase by VE-cadherin promoter |
nbio133 | SCG/ThpNkc | inbred | spontaneous mutation | Faslpr | Rapidly progressive glomerulonephritis | Inbred strain established by sib mating between hybrid strains, BXSB/MpJ (BXSB) female and MRL/MpJ-lpr/lpr (MRL/lpr) male. |
nbio134 | ADAMTS13L/L | congenic | Adamts13 | Thrombotic thrombocytopenic purpura (TTP) | C57BL/6 congenic mice carrying full-length Adamts13 gene derived from 129/Sv | |
nbio135 | ADAMTS13S/S | congenic | Adamts13 | Thrombotic thrombocytopenic purpura (TTP) | 129/Sv congenic mice carrying C-terminal domain deleted Adamts13 gene derived from C57BL/6 | |
nbio136 | MacATF3 Tg #25 | mutant | transgenic | Atf3 (LRG-21) | Metabolic syndrome | Macrophage-specific overexpression of human ATF3 |
nbio137 | MacATF3 Tg #35 | |||||
nbio138 | L1-EGFP#B5 | mutant | transgenic | LINE1, EGFP | Carcinogenesis | Transgenic mice in which human LINE1 retrotransposition can be monitored by EGFP expression |
nbio139 | L1-EGFP#4 | |||||
nbio140 | L1-EGFP#5 | |||||
nbio141 | L1-EGFP#13 | |||||
nbio142 | L1-EGFP#14 | |||||
nbio143 | L1-EGFP#21 | |||||
nbio144 | L1-EGFP#24 | |||||
nbio145 | L1-EGFP#53 | |||||
nbio146 | L1-EGFP#57 | |||||
nbio147 | L1-EGFP#58 | |||||
nbio148 | L1-EGFP#66 | |||||
nbio149 | L1-EGFP#67 | |||||
nbio150 | L1-EGFP#72 | |||||
nbio151 | L1-EGFP#74 | |||||
nbio152 | L1-EGFP#84 | |||||
nbio153 | L1-EGFP#87 | |||||
nbio155 | Zbp1 KO | mutant | knockout | Zbp1 (2010010H03Rik, Dai, mZaDLM) | Infection, Immune abnormality | Knockout of ZBP1 (DAI) |
nbio156 | TBK1, IKKi, TNF KO | mutant | knockout | Tbk1 (1200008B05Rik), Ikki (Ikbke, IKKepsilon), Tnf (DIF, TNF α, TNF-α, Tnfa, TNFα, Tnfsf1a, tumor necrosis factor-α) | Infection, Immune abnormality | Knockout of TBK1, IKKi, TNF genes, NB: Mice with some genotypes are lethal. |
nbio157 | SIK3-KO | mutant | knockout | Sik3 | Obesity, diabetes | SIK3 knockout |
nbio158 | mL1-EFGPm2 | mutant | transgenic | LINE1, EGFP | Carcinogenesis | Transgenic mice in which mouse LINE1 retrotransposition can be monitored by EGFP expression |
nbio159 | mL1-EFGPm14 | |||||
nbio160 | mL1-EFGPm16 | |||||
nbio161 | mL1-EFGPm17 | |||||
nbio162 | mL1-EFGPm30 | |||||
nbio163 | mL1-EFGPm36 | |||||
nbio164 | mL1-EFGPm42 | |||||
nbio165 | mL1-EFGPm55 | |||||
nbio166 | mL1-EFGPf5 | |||||
nbio167 | mL1-EFGPf41 | |||||
nbio168 | mL1-EFGPf44 | |||||
nbio169 | mL1-EFGPf50 | |||||
nbio170 | mL1-EFGPf51 | |||||
nbio171 | mL1-EFGPf59 | |||||
nbio172 | Col11a2-lacZ-dnTgfbr2-#1 | mutant | conditional transgenic | Tgfbr2 | Cartilage anomaly | Chondrocyte-specific expression of dominant-negative TGFβ receptor type II by the Cre/loxP system |
nbio173 | Col11a2-lacZ-dnTgfbr2-#2 | |||||
nbio174 | IRD1 | outbred | spontaneous mutation | Gnat1 | Retinal degeneration | Rod and cone dysfunction |
nbio175 | IRD2 | Rod dysfunction | ||||
nbio176 | LECT2-KO (BALB/cAJcl) | mutant | knockout | Lect2 | Hepatic dysfunction, Rheumatoid Arthritis | LECT2 knockout |
nbio177 | LECT2-KO (C57BL/6JJcl) | |||||
nbio178 | LECT2-Tg12 (BALB/cAJcl) | mutant | transgenic | Lect2 | Hepatic dysfunction, Rheumatoid Arthritis | Systemic overexpression of mouse LECT2 |
nbio179 | LECT2-Tg12 (C57BL/6JJcl) | |||||
nbio180 | LECT2-Tg33 (BALB/cAJcl) | |||||
nbio181 | LECT2-Tg33 (C57BL/6JJcl) | |||||
nbio182 | Rgs16 Knockdown mouse-line #53 | mutant | transgenic | Rgs16 | Abnormal circadian locomotor rhythms | Rgs16 knockdown |
nbio183 | Eisuke | mutant | transgenic | CFP, YFP | Cancer | Expression of EKAREV, the FRET biosensor localized in cytoplasm, which can monitor ERK activity. |
nbio184 | Eisuke-NLS | mutant | transgenic | CFP, YFP | Cancer | Expression of EKAREV-NLS, the FRET biosensor localized in nucleus, which can monitor ERK activity. |
nbio185 | PKAchu | mutant | transgenic | CFP, YFP | Cancer | Expression of AKAR3EV, the FRET biosensor localized in cytoplasm, which can monitor PKA activity. |
nbio186 | PKAchu-NC | mutant | transgenic | CFP, YFP | Cancer | Expression of AKAR3EV-NC, the FRET biosensor |
nbio187 | OH-1 | hybrid | spontaneous mutation | Osteogenesis imperfecta | Spontaneous generation | |
nbio189 | Junko | mutant | transgenic | CFP, YFP | Inflammation | Expression of JNKAREV-NLS, the FRET biosensor localized in nucleus, which can monitor JNK activity. |
nbio190 | Pippi-PI3,4P2 | mutant | transgenic | CFP, YFP, Cdc42 | Cancer, inflammation | Expression of Pippi-PI3,4P2, the FRET biosensor, which can monitor PI3,4P2 level on the plasma membrane. |
nbio191 | Raichu-Cdc42-F0 | mutant | transgenic | CFP, YFP, Cdc42 | Cancer, inflammation | Expression of Raichu-Cdc42, the FRET biosensor, which can monitor Cdc42 activity. |
nbio193 | EdnrA-LacZ | mutant | knockin | Ednra, LacZ | Developmental anomaly of mandible and heart | Visualization for Ednra expression |
nbio194 | EdnrA-EGFP | mutant | knockin | Ednra, EGFP | Developmental anomaly of mandible and heart | Visualization for Ednra expression |
nbio195 | FIR(Flox/+) | mutant | conditional KO | FIR | Cancer | FIR conditional knockout |
nbio196 | B6-SR-PSOX | mutant | knockout | Cxcl16 | Immune abnormality | SR-PSOX/CXCL16 knockout |
nbio197 | BALB-SR-PSOX | mutant | knockout | Cxcl16 | Immune abnormality | SR-PSOX/CXCL16 knockout |
nbio198 | Rolling mouse Nagoya | spontaneous mutation | Cacna1a | Cerebellar ataxia | Mutation in Cacna1a | |
nbio199 | kisimo | mutant | transgenic | Theg | Spermatogenesis failure | Insertion mutation in Theg gene |
nbio201 | FVB/N-Tg(PrPATTCT160)Bay | mutant | transgenic | Atxn10, Prnp | Spinocerebellar ataxia type 10 | Expression of 160 ATTCT repeats under the control of murine prion promoter. |
nbio202 | FVB/N-Tg(PrPATTCT21)Bay | mutant | transgenic | Atxn10, Prnp | Spinocerebellar ataxia type 10 | Expression of 21 ATTCT repeats under the control of murine prion promoter. |
nbio203 | FVB/N-Tg(L7ATTCT160)Bay | mutant | transgenic | Atxn10, Pcp2, GFP | Spinocerebellar ataxia type 10 | Expression of 160 ATTCT repeats under the control of murine L7 promoter. |
nbio204 | FVB/N-Tg(L7ATTCT21)Bay | mutant | transgenic | Atxn10, Pcp2, GFP | Spinocerebellar ataxia type 10 | Expression of 21 ATTCT repeats under the control of murine L7 promoter. |
nbio205 | APG-1 KO | mutant | knockout | Hspa4l | Male infertility | Knockout of Heat shock 70kDa protein 4-like (Hspa4l, also called APG-1) |
nbio206 | APG-2 KO | mutant | knockout | Hspa4 | Knockout of Heat shock 70kDa protein 4 (Hspa4, also called APG-2) | |
nbio207 | CIRP-KO | mutant | knockout | Cirbp | Reduction of undifferentiated spermatogonia | Knockout of Cold inducible RNA binding protein (Cirbp, also called CIRP) |
nbio208 | lox-PKAchu | mutant | transgenic | CFP, YFP, tdKeima | Cancer | Expression of the probe which is consisted of cytoplasm-localized förster (or fluorescence) resonance energy transfer (FRET) biosensor monitoring PKA kinase activity added with lox-tdKeima. |
nbio211 | lox-Eisuke | mutant | transgenic | CFP, YFP, tdKeima | Cancer | Expression of the probe which is consisted of cytoplasm-localized förster (or fluorescence) resonance energy transfer (FRET) biosensor monitoring ERK activity added with lox-tdKeima. |
nbio218 | lox-HRas | mutant | transgenic | CFP, YFP, tdKeima | Cancer | Expression of the probe which is consisted of förster (or fluorescence) resonance energy transfer (FRET) biosensor (Raichu-Ras) monitoring H-Ras kinase activity added with lox-tdKeima. |
nbio221 | lox-Picchu(F0-#1) | mutant | transgenic | CFP, YFP, tdKeima | Cancer | Expression of the probe which is consisted of förster (or fluorescence) resonance energy transfer (FRET) biosensor (Picchu) monitoring the phosphorylation of Crk added with lox-tdKeima. |
nbio222 | lox-Picchu(F1-#1) | |||||
nbio223 | lox-Picchu(F1-#2) | |||||
nbio224 | C57BL/6-Tg(EGFP/E8)Kyo | mutant | transgenic | EGFP, EhV2gp75 ORF E8 | Apoptosis | Production of E8 protein by the recombination of Equine herpesvirus 2 E8 gene from EGFP in the presence of Cre recombinase. |
nbio225 | C57BL/6-TgCasp8tm1DED Tg(EGFP)Kyo | mutant | knockout + transgenic | Casp8, EGFP | Apoptosis | Mating between Caspase-8 knockout mouse and EGFP mouse. |
nbio226 | C57BL/6-Tg(p35/EGFP)Kyo | mutant | transgenic | Myh7, p35, EGFP | Apoptosis | Cardiomyocyte-specific expression of baculovirus p35 and EGFP. |
nbio227 | C57BL/6-Tg(Mx-Cre)Kyo | mutant | transgenic | Mx1, Cre | Interferon-induced GTP-binding protein | Expression of Cre recombinase under the control of mouse Mx1 promoter. |
nbio228 | C57BL/6-Tg(Colα2-Cre)Kyo | mutant | transgenic | Col1a2, Cre | Mesenchymal specificity | Expression of Cre recombinase under the control of mouse Col1α2 promoter. |
nbio229 | NDRG4 KO | mutant | knockout | Ndrg4 | Central nervous system disorder | Ndrg4 knockout |
nbio230 | Tg-Alpha-beta Crystallin(Arg120Gly) | mutant | transgenic | Cryab | Desmin-related cardiomyopathy | Cardiomyocyte-specific expression of CryAB (R120G) which is a point mutant of CryAB (also called HSPB). |
nbio231 | Delta NHE1-TG | mutant | transgenic | SLC9A1 | Cardiac hypertrophy, heart failure | Myocardial-specific overexpression of activated NHE1. |
nbio232 | TgG3S | mutant | transgenic | A4GALT | Fabry disease | Highly expression of α1,4-galactosyltransferase in every tissue. |
nbio233 | Col11a2-hSIK3tg | mutant | transgenic | SIK3 | Osteogenesis and chondrogenesis anomaly | Cartilage-specific expression of human SIK3 under the control of col11a2 promoter/enhancer. |
nbio234 | Derlin-1 KO | mutant | knockout | Derl1 | Embryonic lethality | Derl1 knockout |
nbio235 | Derlin-3 KO | mutant | knockout | Derl3 | ER stress | Derl3 knockout |
nbio236 | Herp KO(B6J) | mutant | knockout | Herpud1 | Cardiovascular disease | Herpud1 knockout |
nbio242 | Herp KO(B6N) | |||||
nbio237 | Bruce | mutant | transgenic | YFP, CFP, tdKeima | Cancer | transgenic mice expressing a probe consisting of lox-tdKeima and cytoplasm-localized FRET biosensor monitoring activity of an enzyme, ataxia telangiectasia mutated (ATM). |
nbio239 | Alb-hSIK3 TG B | mutant | transgenic | SIK3, Alb | Liver diseases | transgenic mice with liver-specific expression of human SIK3 |
nbio240 | Alb-hSIK3 TG C | |||||
nbio244 | TS3; Agouti-revertant; pink | mutant | spontaneous mutation | Hps5 | Chronic diarrhea | Spontaneous mutant mouse model, in which chronic diarrhea continues even if Sodium Dextran Sulfate (DSS) is stopped after diarrhea induction by DSS |
nbio246 | ShDock7 Tg | mutant | transgenic | Dock7 | Peripheral neurodegenerative disease | Systemic knockdown of Dock7 |
nbio247 | Cytohesin-1 KO | mutant | knockout | Cyth1 | Peripheral neurodegenerative disease, hypomyelination | Systemic knockdown of cytohesin-1 |
nbio248 | C57BL/6-Tg(Myh6-EGFP)MG2Tm | mutant | transgenic | Myh6, EGFP | Cardiac specificity | Expression of EGFP under the control of mouse αMHC promoter in the heart. |
nbio249 | C57BL/6-Tg(Myh6-EGFP)MG3Tm | mutant | transgenic | Myh6, EGFP | Cardiac specificity | Expression of EGFP under the control of mouse αMHC promoter in the heart. |
nbio250 | skDNTRPV2-TG | mutant | transgenic | Trpv2, ACTA1 | Muscular diseases | transgenic mice with skeletal-muscle-specific expression of channel-pore mutant proteins (E604K) of transient receptor potential cation channel, subfamily V, member 2 (TRPV2) |
nbio251 | ShDock6 Tg line #1 | mutant | transgenic | Dock6 | Peripheral nerve development | mice with systemic knock-down of Dock6 expression |
nbio252 | Cataract/Nakano | mutant | spontaneous mutation | Cpox | Cataract | spontaneous mutant mice with hereditary cataract |
nbio253 | B6.ICGN-Tenc1 | mutant | spontaneous mutation | Tenc1 (Tensin 2) | Kidney diseases | Tenc1 (tensin 2) deficient mice with C57BL/6J genetic background |
nbio254 | D2.ICGN-Tenc1 | mutant | spontaneous mutation | Tenc1 (Tensin 2) | Kidney diseases | Tenc1 (tensin 2) deficient mice with DBA/2J genetic background |
nbio255 | FVB.Eisuke-NLS | mutant | transgenic | YFP, CFP | Cancer | transgenic mice expressing nucleus-localized FRET biosensor EKAREV-NLS monitoring ERK kinase activity |
nbio256 | ShDock6 Tg line #2 | mutant | transgenic | Dock6 | Peripheral nerve development | mice with systemic knock-down of Dock6 expression |
nbio257 | FAM126A-L53P Tg | mutant | transgenic | FAM126A | Central nervous system | a mouse model for Hypomyelinating leukodystrophies type 5 (HLD5) |
nbio258 | Arhgef19 KO | mutant | conditional KO | Arhgef19 | development | Conditional knockout mice of Arhgef19 gene |
nbio259 | miErbB3 Tg | mutant | transgenic | Erbb3 | Peripheral nerve development | transgenic mice with in vivo knockdown of ErbB3 using a Schwann-cell-specific-promoter-driven production of ErbB3 specific shRNA |
nbio260 | Neuregulin-1 (TypeIII) KO | mutant | knockout | Nrg1 | peripheral nerve development and organogenesis of hearts | knockout mice deficient for type III of Neureglin-1 gene |
nbio261 | Cmah-KO(129) | mutant | knockout | Cmah | Immune disorders | knockout mice deficient for the enzyme cytidine monophospho-N-acetylneuraminic acid hydroxylase (129 background) |
nbio262 | Cmah-KO(B6) | knockout mice deficient for the enzyme cytidine monophospho-N-acetylneuraminic acid hydroxylase (B6 background) | ||||
nbio263 | B3gat1 KO | mutant | knockout | B3gat1 | abnormal high-order functions of the brain | knockout mice deficient for galactosylgalactosylxylosylprotein 3-β-glucuronosyltransferase 1 (B3Gat1, aka., glucuronosyltransferase P, GlcAT-P), a synthetic enzyme of a neural specific carbohydrate antigen, the human natural killer-1 (HNK-1) carbohydrate antigen. |
nbio264 | Pex11a KO | mutant | knockout | Pex11a | obesity, kidney diseases, hepatic steatosis, etc. | knockout mice deficient for Pex11a, a highly expressed gene in the liver and kidney |
nbio265 | microRNA182 KO | mutant | knockout | Mir182 | retina, adipose cell function | knockout mice deficient for MicroRNA-182 (miR-182) gene, which is expressed abundantly in the mammalian retina. |
nbio266 | miArf6 Tg | mutant | transgenic | Arf6 | peripheral nerve development | transgenic mice with in vivo knockdown of Arf6 using a Schwann-cell-specific-promoter-driven production of Arf6 specific shRNA |
nbio267 | B10A.Bcgr | congenic | spontaneous mutation | Slc11a1 | Infectious diseases | congenic mice carrying resistant type (Bcgr) of Nramp1 (Slc11a1) gene with C57BL/10.A genetic background. Slc11a1 determines sensitivity to BCG、Salmonella typhimurium、Leishmania donovani. |
nbio268 | lox-AMPK | mutant | transgenic | YFP, CFP, tdKeima | Cancer | transgenic mice expressing a probe containing lox-tdKeima and FRET biosensor Eevee-AMPK for monitoring AMPK kinase activity |
nbio269 | lox-S6K | mutant | transgenic | YFP, CFP, tdKeima | Cancer | transgenic mice expressing a probe containing lox-tdKeima and FRET biosensor Eevee-S6K for monitoring S6K activity |
nbio270 | C57BL/6-Gt(ROSA)26Sortm1(dach1) | mutant | knockin | Dach1 | Cancer, development | Mice with Cre-inducible expression of Dach1 |
nbio271 | mTSN Tg#2 | mutant | transgenic | Tsn | research in hematopoietic stem cells | transgenic mice expressing CAG-promoter-driven mouse translin (TSN) in the whole body |
nbio272 | mTSN Tg#8 | |||||
nbio273 | mTRAX Tg#4 | mutant | transgenic | Tsnax | developmental abnormality | transgenic mice expressing CAG-promoter-driven mouse trax in the whole body |
nbio274 | FVB.lox-Eisuke-NES | mutant | transgenic | CFP, YFP, tdKeima | Cancer | transgenic mice expressing a cytoplasm-localized FRET biosensor with lox-tdKeima for monitoring ERK kinase activity |
nbio275 | AMPAM | mutant | transgenic | YFP, CFP, tdKeima | Cancer | transgenic mice expressing a cytoplasm-localized FRET biosensor for monitoring AMPK kinase activity |
nbio277 | Sik3-flox | mutant | conditional KO | Sik3 | abnormal metabolism of carbohydrates and lipids | mice with floxed Sik3 alleles, useful for production of conditional knockout mice |
nbio278 | Ddx54 cKO | mutant | conditional KO | Ddx54 | development | mice with floxed Ddx54 alleles, useful for production of conditional knockout mice |
nbio279 | C57BL/6J-Pros1 K196E NCVC | congenic | knockin | Pros1 | thromboembolism | knock-in mice carrying c.586A>G (p.K196E) mutation introduced in Pros1 locus of C57BL/6 mice |
nbio280 | 129+Ter/Sv-Pros1 K196E NCVC | congenic | knockin | Pros1 | thromboembolism | knock-in mice carrying c.586A>G (p.K196E) mutation introduced in Pros1 locus of 129+Ter/Sv mice |
nbio281 | C57BL/6J-Plg A622T NCVC | mutant | knockin | Plg | thromboembolism | knock-in mice carrying c.1864G>A (p.A622T) mutation introduced in Plg locus of C57BL/6J mice |
nbio282 | C57BL/6J-Pros1 K196E + Plg A622T NCVC | mutant | knockin | Pros1, Plg | thromboembolism | C57BL/6J mice carrying two knockin alleles (both Pros1 K196E and Plg A622T mutations) |
nbio283 | Balb/c.PKAchu | mutant | transgenic | CFP, YFP | Cancer | BALB/c mice expressing AKAR3EV-NC, FRET biosensors for monitoring PKA activity |
nbio284 | Balb/c.Eisuke-NES | mutant | transgenic | YFP, CFP | Cancer | BALB/c mice expressing cytoplasm-localized FRET biosensors EKAREV-NES for monitoring ERK kinase activity |
nbio285 | Balb/c.lox-tdKeima-PKAchu | mutant | transgenic | CFP, YFP, tdKeima | Cancer | BALB/c mice expressing cytoplasm-localized förster (or fluorescence) resonance energy transfer (FRET) biosensors with lox-tdKeima for monitoring PKA kinase activity. |
nbio286 | Hsp60 Tg line #004 | mutant | transgenic | HSPD1 | neurological disorders | transgenic mice with overexpression of a HSP60 mutant (D25G) in tissues expressing myelin basic protein (MBP) |
nbio287 | Hsp60 Tg line #017 | |||||
nbio288 | DgkβKO | mutant | knockout | Dgkb | neurological disorders | knockout mice deficient for diacylglycerol kinase, beta (Dgkβ) gene |
nbio289 | Kuro | mutant | spontaneous mutation | unknown | Alopecia, abnormal pigmentation | Spontaneous mutant strain with air loss and dark skin |
nbio290 | C57BL/6J-Pros1 KO NCVC | congenic | knockout | Pros1 | thromboembolism | knockout C57BL/6 mice deficient for Pros1 gene |
nbio291 | C57BL/6J-Pros1 KO + Plg A622T NCVC | mutant | knockout + knockin | Pros1, Plg | thromboembolism | C57BL/6J mice carrying Pros1 knockout alleles and and Plg A622T knockin alleles |
nbio293 | FVB.ICGN-Tenc1 | congenic | spontaneous mutation | Tenc1 (Tensin 2) | kidney diseases | congenic mice carrying mutated Tenc1 (Tensin2) with FVB genetic background. The mice show rapid and severe glomerular diseases. |
nbio294 | CBy.ICGN-Tenc1 | congenic | spontaneous mutation | Tenc1 (Tensin 2) | kidney diseases | congenic mice carrying mutated Tenc1 (Tensin2) with BALB/cBy genetic background |
nbio295 | 129.ICGN-Tenc1 | congenic | spontaneous mutation | Tenc1 (Tensin 2) | kidney diseases | congenic mice carrying mutated Tenc1 (Tensin2) with 129+Ter/Sv genetic background |
nbio296 | ACE2 Tg #5 | mutant | transgenic | ACE2 | infectious diseases | transgenic mice carrying CAG-promoter-driven human angiotensin I converting enzyme 2 (hACE2), a receptor for SARS Coronavirus (SARS-CoV) |
nbio297 | ACE2 Tg #16 | |||||
nbio298 | ACE2 Tg #17 | |||||
nbio299 | PGC-1α-b/A-line | mutant | transgenic | Ppargc1a (PGC-1α) | Luft's disease (mitochondrial myopathy) | Muscle-specific overexpression of mouse PGC-1α-b mRNA (2 lines) |
nbio300 | PGC-1α-b/B-line | |||||
nbio301 | PGC-1α-c/A-line | mutant | transgenic | Ppargc1a (PGC-1α) | Luft's disease (mitochondrial myopathy) | Muscle-specific overexpression of mouse PGC-1α-c mRNA (3 lines) |
nbio302 | PGC-1α-c/B-line | |||||
nbio303 | PGC-1α-c/C-line | |||||
nbio304 | C57BL/6N.129/SvJ-Slc43a1tm1 | mutant | knockout | Slc43a1 | Research on CD98 | Knockout mice deficient for Slc43a1 gene |
nbio305 | C57BL/6N.129/SvJ-Slc3a2tm1 | mutant | conditional KO | CD98hc (Slc3a2) | Research on CD98 | Mice carrying floxed exon 3 of Slc3a2 gene |
nbio306 | C57BL/6N.129/SvJ-Slc7a5tm1 | mutant | conditional KO | Slc7a5 | Research on CD98 | Mice carrying floxed exon 3 of Slc7a5 gene |
nbio307 | TH-Luc 176 | mutant | transgenic | Th | Toxicity research of dioxins | Transgenic mice (three sublines) expressing c-myc-tagged luciferase driven by Th enhancers (AHRE-III) and Th promoter. |
nbio308 | TH-Luc 177 | |||||
nbio309 | TH-Luc 183 | |||||
nbio310 | Conditional KI (XIAP) | mutant | conditional knock-in | Xiap | apoptosis research | This strain is a conditional knock-in strain carrying a floxed spacer insertion in the Xiap gene. The Xiap gene will express in pups from the mice mated with Cre-expressed mice. |
nbio311 | Conditional KO (Cytohesin-2) | mutant | conditional knock-out | Cyth2 | Signal transduction research | This strain of mice has a floxed exon in Cyth2 gene. The Cyth2 gene can be silenced (knocked out) by the mating with Cre mice. |
nbio312 | C57BL6/J (MHC-MCM-V2K) | mutant | conditional knock-out | Trpv2 | Ca Channel research | Mice in which heart-specific Trpv2 knockout can be induced by tamoxifen treatment. |
nbio313 | C57BL/6J(V2D) | mutant | knock-out | Trpv2 | Ca channel research | Mice heterozygous for Trpv2 knockout alleles. |
nbio314 | C57BL/6J(V2K) | mutant | conditional knock-out | Trpv2 | Ca channel research | Conditional knock-out mice (TRPV2FL/FL) in which TRPV2 can be silenced by crosses with Cre mice. |
nbio315 | Conditional KO (CD69) | mutant | conditional knock-out | Cd69 | Cancer research | Conditional knock-out mice in which Cd69 can be silenced by crosses with Cre mice. |
nbio316 | Conditional KO (14-3-3 epsilon) | mutant | conditional knock-out | Ywhae (14-3-3 epsilon) | Neuronal disease research | Conditional knock-out mice in which 14-3-3 epsilon can be silenced by crosses with Cre mice. |
nbio317 | villin-CXCL12 Tg | mutant | transgenic | Cxcl12 | Research in epithelial cell inflammation of intestines | Transgenic mice with gastrointestinal-epithelial-cell-specific overexpression of mouse CXCL12 (SDF-1α) under the control of mouse villin promoter |
nbio318 | B6 Albino-PKAchu | mutant | transgenic | CFP, YFP | Cancer | A transgenic line expressing a CAG-promotor-driven, cytoplasm-localized forster (or fluorescence) resonance energy transfer (FRET) biosensor (AKAREV) for monitoring PKA kinase activity (C57BL/6 with albino and hairless mutations) |
nbio319 | B6 Albino-PKAchu-NC | mutant | transgenic | CFP, YFP | Cancer | A transgenic line expressing a CAG-promotor-driven, negative-control-type forster (or fluorescence) resonance energy transfer (FRET) biosensor (AKAREV-NC) lacking monitoring activity for PKA kinase activity (C57BL/6 with albino and hairless mutations). |
nbio320 | B6 Albino-lox-tdKeima-PKAchu | mutant | transgenic | CFP, YFP, tdKeima | Cancer | A transgenic line expressing a CAG-promotor-driven, cytoplasm-localized forster (or fluorescence) resonance energy transfer (FRET) biosensor for monitoring PKA kinase activity in combination with lox-tdKeima (C57BL/6 with albino and hairless mutations) |
nbio322 | Conditional KO (Kcnk9) | mutant | conditional KO | Kcnk9 (Task3) | Ion channel research | Conditional knockout mice for Kcnk9 (Task3) |
nbio323 | B6.ICGN-C1raC1s1C1rb | mutant | congenic | C1ra, C1s1, C1rb | Immune disorders | Mice of the strain have mutations in C1 (a component of classical complement pathway) alleles, i.e., complete deletion of C1s1 and partial deletions of C1ra and C1rb. |
nbio324 | D2.ICGN-C1raC1s1C1rb | |||||
nbio325 | hyBRET-ERK-NES | mutant | transgenic | CFP, YFP, Rluc | Cancer | A transgenic mouse line expressing CAG-promoter-driven, cytoplasm-localized hyBRET biosensors monitoring ERK kinase activity. |
nbio326 | hyBRET-ERK-NLS | mutant | transgenic | CFP, YFP, Rluc | Cancer | A transgenic mouse line expressing CAG-promoter-driven, nucleus-localized hyBRET biosensors monitoring ERK kinase activity. |
nbio327 | hyBRET-AMPK | mutant | transgenic | CFP, YFP, Rluc | Cancer | A transgenic mouse line expressing CAG-promoter-driven, cytoplasm-localized hyBRET biosensors monitoring AMPK kinase activity. |
nbio328 | hyBRET-S6K | mutant | transgenic | CFP, YFP, Rluc | Cancer | A transgenic mouse line expressing CAG-promoter-driven, cytoplasm-localized hyBRET biosensors monitoring S6K kinase activity. |
nbio330 | BIG1 (Arfgef1) cKO | mutant | conditional KO | BIG1(Arfgef1) | Vesicular trafficking | Conditional knockout mice for BIG1 (Arfgef1) gene |
nbio331 | Arf1 cKO | mutant | conditional KO | Arf1 | Vesicular trafficking | Conditional knockout mice for Arf1 gene |
nbio332 | ERK-NES-B6 Albino | mutant | transgenic | CFP, YFP | Cancer | A transgenic line expressing a CAG-promotor-driven, cytoplasm-localized forster (or fluorescence) resonance energy transfer (FRET) biosensor (AKAREV) for monitoring ERK kinase activity (C57BL/6 with albino and hairless mutations). |
nbio333 | ERK-NLS-B6 Albino | mutant | transgenic | CFP, YFP | Cancer | A transgenic line expressing a CAG-promotor-driven, nucleus-localized forster (or fluorescence) resonance energy transfer (FRET) biosensor (AKAREV) for monitoring ERK kinase activity (C57BL/6 with albino and hairless mutations). |
nbio334 | nNOS-Cre-knockin | mutant | Knock-in | nNos, Cre | neurological disorders | Knock-in mice with Cre-SV40 polyA sequence at the start codon of Exon1 of nNOS gene |
nbio335 | Conditional KO (plexin B3) | mutant | conditional KO | Plxnb3 | Central nervous system | Plxnb3-floxed mice for production of Plxnb3 knockout mice |
nbio337 | Hps5-KO | mutant | knockout | Hps5 | Abnormal pigmentation | A mouse strain in which Hps5, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio338 | Vgll2-KO | mutant | Knockout | Vgll2 | Muscular diseases | Vestigial like family member 2 (Vgll2) gene knockout mice |
nbio339 | Nxf2-KO | mutant | Knockout | Nxf2 | Meiosis | nuclear RNA export factor 2 (Nxf2) gene knockout mice |
nbio340 | Hairless 4C30 | mutant | Knockout/transgenic | Hr,St3gal2 (Siat5, St3GalII) | Dilated cardiomyopathy | Dilated cardiomyopathy model (4C30) with hairless mutation |
nbio341 | MBP-Cre-Knockin | mutant | Knock-in | Mbp, Cre | Myeline generative diseases | Knock-in mice with Cre-SV40 polyA sequence at the start codon of Exon1 of myelin basic protein (MBP) gene |
nbio342 | Hps3-KO | mutant | knockout | Hps3 | Abnormal pigmentation | A mouse strain in which Hps3, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio343 | CD72flox | mutant | conditional KO | Cd72 | Immune abnormality | CD72-floxed mice for production of CD72 knockout mice showing a relatively severe SLE-like autoimmune disease |
nbio344 | CD72Y7F | mutant | knock-in | Cd72 | Immune abnormality | Mice expressing mutant CD72Y7F, which show a relatively severe SLE-like autoimmune disease. |
nbio345 | DDX54-flox | mutant | conditional KO | Ddx54 | Development | Mice with floxed Ddx54 alleles, useful for production of conditional knockout mice |
nbio346 | Conditional KI (Bim) | mutant | conditional KI | Bim | Apoptosis | Conditional knockin mice for the Bim gene |
nbio347 | Tomm5 KO | mutant | knockout | Tomm5 | Mitochondria function, pulmonary fibrosis | Tomm5 knockout mice |
nbio348 | Trp53 KO | mutant | Knockout | Trp53 | oncology, pulmonary fibrosis | Trp53 knockout mice |
nbio349 | Tnfrsf1a KO | mutant | Knockout | Tnfrsf1a | TNF receptor-related periodic syndrome, pulmonary fibrosis | Tnfrsf1a knockout mice |
nbio350 | Tnfrsf1b KO | mutant | Knockout | Tnfrsf1b | TNF-induced inflammation and immune response, pulmonary fibrosis | Tnfrsf1b knockout mice |
nbio351 | Importin α3 / KPNA3 KO | mutant | Knockout | Kpna3 | Nuclear transport | Importin α3 (KPNA3) knockout mice |
nbio352 | Importin α4 / KPNA4 KO | mutant | Knockout | Kpna3 | Nuclear transport | Importin α4 (KPNA4) knockout mice |
nbio353 | Sik3-flox (Neo-) | mutant | conditional KO | Sik3 | abnormal metabolism of carbohydrates and lipids | Mice with floxed Sik3 alleles, useful for production of conditional knockout mice (Neo cassette removed) |
nbio354 | Mup-KO | mutant | Knockout | Mup cluster | Urinary proteins / pheromone | Major urinary protein (Mup) gene cluster knockout mice |
nbio355 | Hsp1-KO | mutant | knockout | Hsp1 | Abnormal pigmentation | A mouse strain in which Hps1, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio356 | Ap3b1-KO | mutant | Knockout | Ap3b1 | Abnormal pigmentation | A mouse strain in which Ap3b1, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio357 | Hps4-KO | mutant | Knockout | Hps4 | Abnormal pigmentation | A mouse strain in which Hps4, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio358 | Hps6-KO | mutant | knockout | Hps6 | Abnormal pigmentation | A mouse strain in which Hps6, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio359 | Dtnbp1-KO | mutant | knockout | Dtnbp1 | Abnormal pigmentation | A mouse strain in which Dtnbp1, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio360 | Bloc1s3-KO | mutant | knockout | Bloc1s3 | Abnormal pigmentation | A mouse strain in which Bloc1s3, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio361 | Bloc1s6-KO | mutant | knockout | Bloc1s6 | Abnormal pigmentation, torticollis | A mouse strain in which Bloc1s6, one of the genes responsible for Hermansky-Pudlak syndrome (HPS), was knocked out. |
nbio362 | TIGAR KO | mutant | knockout | Tigar | Cardiac energy metabolism | TP53-induced glycolysis and apoptosis regulator (Tigar) gene kncokout mice |
nbio363 | αMHC TIGAR KO (-/-) Cre(-) | mutant | conditional KO | Tigar | Cardiac energy metabolism | Mice with floxed Tigar alleles, useful for production of conditional knockout mice |
nbio364 | Dglucy cKO | mutant | conditional KO | Dglucy | D-Glutamate metabolism | Mice with floxed Dglucy alleles, useful for production of conditional knockout mice |
nbio365 | Dglucy-KO | mutant | knockout | Dglucy | D-Glutamate metabolism | D-Glutamate cyclase (Dglucy) gene kncokout mice |
nbio366 | Dglucy-TG | mutant | transgenic | Dglucy | D-Glutamate metabolism | Transgenic mice with heart-specific expression, driven by mouse α-MHC promoter, of the Dglucy gene. |
nbio367 | Ctsk-KO | mutant | knockout | Ctsk | Pulmonary fibrosis, osteosclerotic diseases | Cathepsin K (Ctsk) gene knockout mice |
nbio368 | Cysltr2-KO | mutant | knockout | Cysltr2 | Pulmonary fibrosis, bronchial asthma | Cysteinyl leukotriene receptor 2 (Cysltr2) gene knock out mice |
nbio369 | Sftpa1-KO | mutant | knockout | Sftpa1 | Pulmonary fibrosis | Knockout mice of surfactant-associated protein a1 (SFTPA1), a lung surfactant protein. |
nbio370 | B6N Albino-Blvra-/- | mutant | knockout | Blvra | Cancer | Biliverdin Reductase-A (Blvra) knockout mice |
nbio371 | B6N lox-Booster-PKAchu | mutant | transgenic | mCherry, mKate2, mKOκ | Cancer | Transgenic mice expressing a probe with lox-mCherry-NLS added upstream of a cytoplasmically-localized FRET biosensor (Booster-PKA) that monitors the kinase activity of PKA. |
nbio372 | B3gat2 KO | mutant | knockout | B3gat2 | Sugar chain synthesis | B3gat2 (GlcAT-S) knockout mice |
nbio373 | PKAchu Gnat1-/- | mutant | transgenic/KO | CFP, YFP, Gnat1 | Cancer | Gnat1-KO mice with expression of AKAR3EV, the FRET biosensor localized in cytoplasm, which can monitor PKA activity. |
nbio374 | Swsap1-KO | mutant | Knockout | Swasp1 | Research in DNA repair | Swsap1 knockout mice |
nbio375 | SUN1-mOrange | mutant | Transgenic (Rosa26-KI) | Sun1, mOrange | Research in nuclear membranes | Rosa26-knock-in mice systemically expressing a fusion gene of the SUN1 and mOrange |
nbio376 | Ct55-KO | mutant | Knockout | Ct55 | Cancer | Ct55 knockout mice |
nbio377 | Ccdc83-KO | mutant | Knockout | Ccdc83 | Cancer | Ccdc83 knockout mice |
nbio379 | Cftr-KO | mutant | Knockout | Cftr | Cystic fibrosis | Cftr knockout mice |
nbio380 | Fcgr1-KO | mutant | Knockout | Fcgr1 | Immunology | Knockout mice lacking Fcgr1 gene |
nbio381 | Fcgr234-KO | mutant | Knockout | Fcgr2b, Fcgr3, Fcgr4 | Immunology | Knockout mice lacking Fcgr2b,Fcgr3 and Fcgr4 genes |
nbio384 | Hck-KO | mutant | Knockout | Hck | Pulmonary fibrosis,Myeloproliferative disorders | Hck knockout mice |
nbio386 | Sftpd-KO | mutant | Knockout | Sftpd | Pulmonary fibrosis | Sftpd knockout mice |
nbio387 | Cav1-KO | mutant | Knockout | Cav1 | Pulmonary fibrosis | Cav1 knockout mice |
nbio388 | Ace2-KO | mutant | Knockout | Ace2 | Hypertension, Covid-19 | Ace2 knockout mice |
nbio389 | L-PGDS TG #B-7 | mutant | transgenic | Ptgds | Prostaglandin synthesis | Transgenic mice that systemically express human lipocalin-type prostaglandin synthase (L-PGDS). |
nbio390 | L-PGDS TG #B-17 | |||||
nbio391 | L-PGDS TG #B-20 | |||||
nbio392 | B6/lprC1scg | mutant | Congenic | part of chromosome 1 in SCG/Kj mice | spontaneous lupus nephritis, vasculitis | Congenic mice with spontaneous lupus nephritis, vasculitis, and MPO-ANCA production (derived from SCG/Kj mice) |
nbio402 | C3H/HeN-Kusa-TgH(TnC) | mutant | Knockout | Tnc | Tenascin C | Congenic strain carrying tenascin C (Tnc) knockout alleles with C3H/HeN genetic background. |
nbio405 | TNKO-kusa | mutant | Knockout | Tnc | Tenascin C | Tenascin-C gene knockout mice |
nbio406 | hyBRET-AMPK (B6) | mutant | transgenic | CFP, YFP, Rluc | Cancer | Mice with C57BL/6J genetic background of hyBRET-AMPK (nbio327, genetic background: B6-Albino). | nbio408 | Aspa-KO | mutant | Knockout | Aspa | Neurological disorders | Knockout mice of the Aspa gene, the causative gene of Canavan disease. |
nbio409 | Eif2b1-KO | mutant | Knockout | Aspa | Neurological disorders | Knockout mice of the Eif2b1 gene, one of the causative genes of progressive leukoencephalopathy. |
nbio410 | Conditional KO (Dhps) | mutant | conditional KO | Dhps | Cancer | Conditional knockout mice of Dhps gene |
nbio412 | flox-LPGDS | mutant | knockout | Ptgds | Prostaglandin synthesis | Conditional knockout mice of lipocalin-type prostaglandin synthase (L-PGDS) gene |
nbio413 | Mlc1-KO | mutant | knockout | Mlc1 | Neurological disorders | Knockout mice of the Mlc1 gene, one of the causative genes of progressive leukoencephalopathy. |
nbio416 | Tmppe-KO | mutant | knockout | Tmppe | TMPPE protein analysis | Knockout mice of the Tmppe gene |
nbio417 | Glb1E6-KO | mutant | knockout | Glb1 | GM1 gangliosidosis | Knockout mice of the Glb1 gene produced by genome editing. |
nbio420 | Eif2b5-KO | mutant | knockout | Eif2b5 | Neurological disorders | Knockout mice of the Eif2b5 gene, one of the causative genes of progressive leukoencephalopathy. |
nbio421 | Gnat1-/- RPE65Leu450 | mutant | knockout | Gnat1Rpe65 | Photoreceptor Research | Mice deficient in the rod transducin α subunit (Gnat1). |
nbio422 | L-PGDS-KO | mutant | knockout | Ptgds(L-PGDS) | Neurological disorders | Lipocalin-type PGD synthase (L-PGDS)-deficient mice. |
nbio423 | H-PGDS-KO | mutant | knockout | Hpgds(H-PGDS) | Neurological disorders | Hematopoietic PGD synthase (HPGDS)-deficient mice. |
nbio424 | L-PDGS-H-PGDS-dKO | mutant | knockout | Ptgds(L-PGDS), Hpgds(H-PGDS) | Neurological disorders | Double knockout mice lack both lipocalin-type and hematopoietic-type PGD synthases. |
nbio425 | Cyth2-KI | mutant | knockout | Cyth2 | Neurological disorders | Knockin mice with a Y381F mutation in cytohesin-2. |
nbio428 | Bicc1-KO | mutant | knockout | Bicc1 | Cystic kidney | Knockout mice of the Bicc gene produced by genome editing. |
nbio429 | Muc1-KO | mutant | knockout | Muc1 | Cystic kidney | Knockout mice of the Muc1 gene produced by genome editing. |
nbio430 | Aars2-flox | mutant | conditional knockout | Aars2 | Neurological disorders | Floxed mice of the Aars2 gene, one of the causative genes for progressive leukoencephalopathy. |
nbio444 | parchorin#143 | mutant | conditional knockout | Clic6 | Ion channel research | Floxed mice for conditional kncokout of the parchorin (CLIC6) gene. |
nbio445 | dNeodExparchorin#103 | mutant | knockout | Clic6 | Ion channel research | Parchorin (CLIC6) gene knockout mice. |
nbio446 | dNeodExparchorin#143 | mutant | knockout | Clic6 | Ion channel research | Parchorin (CLIC6) gene knockout mice. |
nbio454 | Xylt2-KO | mutant | knockout | Xylt2 | Cystic kidney | Knockout mice of the Xylt2 gene produced by genome editing. |
nbio455 | Umod-KO | mutant | knockout | Umod | Cystic kidney | Knockout mice of the Umod gene produced by genome editing. |
nbio456 | Anks6-KO | mutant | knockout | Anks6 | Cystic kidney | Knockout mice of the Anks6 gene produced by genome editing. |