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Strain Detail: FVB.ICGN-Tenc1 mice

Strain information
Resource No. nbio293
Strain name FVB.ICGN-Tenc1
Strain Nomenclature
Common name/Synonyms FVBGN
Strain types congenic
Background strain FVB/N Jcl
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Kozue Uchio
Depositor Kozue Uchio
Conditions of distribution In publishing the research results obtained by use of the biological resource, a citation of the following literature (ref. 1) is requested. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

The FVB.ICGN-Tenc1 mice are congenic mice carrying mutated Tenc1 (Tensin2) with FVB genetic background. The mutated Tenc1 was derived from ICGN mice (nbio004). The FVB.ICGN-Tenc1 mice develop severe glomerular disease. The strain is useful for research in kidney diseases.
Reference(s)
  1. Uchio-Yamada K, Monobe Y, Akagi K, Yamamoto Y, Ogura A, and Manabe N. (2016) Tensin2-deficient mice on FVB/N background develop severe glomerular disease. J Vet Med Sci 78(5):811-8. [PMID:26854109]
  2. Uchio-Yamada K, Sawada K, Tamura K, Katayama S, Monobe Y, Yamamoto Y, Ogura A, and Manabe N. (2013) Tenc1-deficient mice develop glomerular disease in a strain-specific manner. Nephron Exp Nephrol 123(3-4):22-33. [PMID:23988887]
Resource information
Cryopreserved sperm In-house Genotype
Medium
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype
Medium
From other institutions Mating System
Genotype
Method
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals Live animals only (Pleasecontasct us.)
Gene information
Mutation types spontaneous mutation
Gene symbol Tenc1
Gene name tensin like C1 domain-containing phosphatase
Genotyping information