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Strain Detail: Fcgr234-KO mice

Strain information
Resource No. nbio381
Strain name Fcgr234-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Mice in which Fcgr2b, Fcgr3, and Fcgr4, which constitute the receptor protein for the Fc site of the immunoglobulin molecule, were knocked out at once. Guide RNAs were set in two places so as to sandwich all three genes, and the nucleotides between them was deleted by genome editing. It is useful for the study of acquired immunity.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types knockout
Gene symbol Fcgr2b, Fcgr3, Fcgr4
Gene name [Fc receptor, IgG, low affinity IIb], [Fc receptor, IgG, low affinity III], and [Fc receptor, IgG, low affinity IV]
Genotyping information