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Strain Detail: Aspa-KO mice

Strain information
Resource No. nbio408
Strain name Aspa-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Knockout mice of the Aspa gene, the causative gene of Canavan disease. Exon 2 of the Aspa gene was deleted by applying two guide RNAs simultaneously to introns 1 and 2 of the Aspa gene. It is useful in the study of Canavan disease.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types knockout
Gene symbol Aspa
Gene name aspartoacylase
Genotyping information