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Strain Detail: Eif2b1-KO mice

Strain information
Resource No. nbio409
Strain name Eif2b1-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Knockout mice of the Eif2b1 gene, one of the causative genes of progressive leukoencephalopathy. Exons 3 and 4 of the Eif2b1 gene were deleted by applying two guide RNAs simultaneously to introns 2 and 4 of the Eif2b1 gene. It is useful in the study of progressive leukoencephalopathy.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types knockout
Gene symbol Eif2b1
Gene name eukaryotic translation initiation factor 2B, subunit 1 (alpha)
Genotyping information