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Strain Detail: BIG1 (Arfgef1) cKO mice

Strain information
Resource No. nbio330
Strain name BIG1 (Arfgef1) cKO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain
Institution University of Pharmacy and Life Sciences
Developer Junji Yamauchi
Depositor Junji Yamauchi
Conditions of distribution

Collaboration with the depositor only. In publishing the research results obtained by use of the biological resource, a citation of the following literature and the stipulation of an acknowledgment to depositor are requested. It's necessary to obtain depositor's consent on use of biological resources. contact us

Animal Health Report
Strain description Conditional knockout mice for BIG1 (Arfgef1) gene.
  1. Miyamoto Y, Torii T, Tago K, Tanoue A, Takashima S, Yamauchi J (2018) BIG1/Arfgef1 and Arf1 regulate the initiation of myelination by Schwann cells in mice. Sci Adv 4(4):eaar4471. [PMID:29740613]
Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System IVF
Medium EFS40
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol BIG1 (Arfgef1)
Gene name ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited)
Genotyping information