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Strain Detail: C57BL/6N.129/SvJ-Slc7a5tm1 mice
|Institution||Division of Laboratory Animal Resources, National Research Institute for Child Health and Development|
|Conditions of distribution||
It's necessary to obtain depositor's consent on use of biological resources.Contact us. Users of this strain have to include the depositor as a co-author in users' first scientific paper using this strain.
|Animal Health Report|
The C57BL/6N.129/SvJ-Slc7a5tm1 is a conditional knockout mouse strain, which was produced with floxed exon 3 of Slc7a5 gene. Researchers can induce conditional KO in the Slc7a5 gene by crossing mice with Cre recombinase expression. This strain was derived from ES cells with 129 background (EW4 cell line) and then backcrossed to C57BL/6N mice (N=17 at introduction into NIBIOHN).
|From other institutions||Genotype|
|Cryopreserved embryo||In-house||Mating System||IVF|
|Genotype||mix of KO/+ and wild-type|
|From other institutions||Mating System|
|Strain status / Availability||Cryopreserved sperm||Within 1 month|
|Cryopreserved embryo||Within 1 month|
|Live animals||Approx. 2 months|
|Mutation types||Conditional knockout|
|Gene name||solute carrier family 7 (cationic amino acid transporter, y+ system), member 5|