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Strain Detail: C57BL/6N.129/SvJ-Slc7a5tm1

Strain information
Resource No. nbio306
Strain name C57BL/6N.129/SvJ-Slc7a5tm1
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain
Institution Division of Laboratory Animal Resources, National Research Institute for Child Health and Development
Developer Hideki Tsumura
Depositor Hideki Tsumura
Conditions of distribution

It's necessary to obtain depositor's consent on use of biological resources. Contact us. Users of this strain have to include the depositor as a co-author in users' first scientific paper using this strain.

Animal Health Report
Strain description

The C57BL/6N.129/SvJ-Slc7a5tm1 is a conditional knockout mouse strain, which was produced with floxed exon 3 of Slc7a5 gene. Researchers can induce conditional KO in the Slc7a5 gene by crossing mice with Cre recombinase expression. This strain was derived from ES cells with 129 background (EW4 cell line) and then backcrossed to C57BL/6N mice (N=17 at introduction into NIBIOHN).

    Resource information
    Cryopreserved sperm In-house Genotype Heterozygous
    Medium FERTIUP
    From other institutions Genotype
    Cryopreserved embryo In-house Mating System IVF
    Genotype mix of KO/+ and wild-type
    Medium EFS40
    From other institutions Mating System
    Strain status / Availability Cryopreserved sperm Within 1 month
    Cryopreserved embryo Within 1 month
    Live animals Approx. 2 months
    Gene information
    Mutation types Conditional knockout
    Gene symbol Slc7a5
    Gene name solute carrier family 7 (cationic amino acid transporter, y+ system), member 5
    Genotyping information