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Strain Detail: Cav1-KO mice

Strain information
Resource No. nbio387
Strain name Cav1-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Mitsuho Sasaki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Knockout mice of Caveolin 1 (CAV1), a major component of the cell membrane caveola. They were created by introducing a stop codon by inserting a single base into Exon 3 of the Cav1 gene by genome editing. It is expected to be used as a model for pulmonary fibrosis.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types knockout
Gene symbol Cav1
Gene name Caveolin 1
Genotyping information