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Strain Detail: Sik3-flox (Neo-) mice

Strain information
Resource No. nbio353
Strain name Sik3-flox (Neo-)
Strain Nomenclature
Common name/Synonyms floxed Sik3 (Neo-)
Strain types mutant
Background strain C57BL/6J
Institution Neuroscience and Pathobiology, Research Institute of Environmental Medicine´╝îNagoya University
Developer Dr. Naoto Hayasaka
Depositor Dr. Naoto Hayasaka
Conditions of distribution It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Salt Inducible Kinase 3 (Sik3) is a protein kinase belonging to the AMP-dependent kinase family. The Sik3-flox mice have floxed Sik3 alleles and can be used to produce conditional knockout mice for the Sik3 gene. This strain differs from nbio277 in that the Neo cassette has been removed by mating with flippase-expressing mice.

Reference(s)
Resource information
Cryopreserved sperm In-house Genotype homozygous
Medium
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype heterozygous
Medium
From other institutions Mating System
Genotype
Method
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types conditional KO
Gene symbol Sik3
Gene name Salt Inducible Kinase 3
Genotyping information