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Strain Detail: D2.ICGN-Tenc1 mice

Strain information
Resource No. nbio254
Strain name D2.ICGN-Tenc1
Strain Nomenclature D2GN
Common name/Synonyms
Strain types mutant, congenic
Background strain DBA/2J Jcl
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Kozue Uchio
Depositor Kozue Uchio
Conditions of distribution In publishing the research results obtained by use of the biological resource, a citation of the following literature (ref. 1) is requested. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

The D2.ICGN-Tenc1 mice are congenic mice carrying mutated Tenc1 (Tensin2) with DBA/2J genetic background. The mutated Tenc1 was derived from ICGN mice (nbio004). The D2.ICGN-Tenc1 strain is useful as a mouse model for kidney diseases.

  1. Uchio-Yamada K, Sawada K, Tamura K, Katayama S, Monobe Y, Yamamoto Y, Ogura A, and Manabe N. (2013) Tenc1-deficient mice develop glomerular disease in a strain-specific manner. Nephron Exp Nephrol 123(3-4):22-33. [PMID:23988887]
Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals Live animals only (Please contasct us.)
Gene information
Mutation types spontaneous mutation
Gene symbol Tenc1
Gene name tensin like C1 domain-containing phosphatase
Genotyping information