HOME > mice > Swsap1 KO mice
Strain Detail: Swsap1 KO mice
| Strain information |
| Resource No. |
nbio374 |
| Strain name |
Swsap1 KO |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
C57BL/6 |
| Institution |
Lab. of Genome-Chromosome Functions, Institute for Protein Research, Osaka University |
| Developer |
Akira Shinohara |
| Depositor |
Akira Shinohara |
| Conditions of distribution |
Users shall cite references specified by the depositor when publishing research results. Users shall give an acknowledgment to the depositor when publishing the research results. Users shall obtain the consent of the depositor in advance. contact us |
| Animal Health Report |
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| Strain description |
Knockout mice for the Swsap1 gene. SWSAP1 is suggested to protect RAD51 filaments by antagonizing the anti-recombinase, FIGNL1 (Ref. 1). This strain is useful for studying DNA repair. |
| Reference(s) |
- Matsuzaki K, Kondo S, Ishikawa T, and Shinohara A. (2019) Human RAD51 paralogue SWSAP1 fosters RAD51 filament by regulating the anti-recombinase FIGNL1 AAA+ ATPase. Nat Commun 10(1):1407. [PMID:30926776]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
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| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
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| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
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| Cryopreserved embryo |
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| Live animals |
Only live mice are available (Approx. 2 months). |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Swsap1 |
| Gene name |
SWIM type zinc finger 7 associated protein 1 |
| Genotyping information |
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