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Strain Detail: APG-1 KO mice

Strain information
Resource No. nbio205
Strain name APG-1 KO
Strain Nomenclature C57BL/6-Hspa4ltm1cmbKyo
Common name/Synonyms
Strain types mutant
Background strain
Institution Department of Clinical Molecular Biology, Graduate School of Medicine, Kyoto University
Depositor Jun Fujita
Conditions of distribution It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

APG-1 KO mice are knockout mice of Heat shock 70kDa protein 4-like (Hspa4l, also called APG-1), a member of Hsp110 family.

  1. Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K, and Fujita J. (2019) Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Sci Signal 12(574):. [PMID:30914484]
Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Hspa4l
Gene name heat shock 70kDa protein 4-like
Genotyping information