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Strain Detail: APG-1 KO mice

Strain information
Resource No. nbio205
Strain name APG-1 KO
Strain Nomenclature C57BL/6-Hspa4ltm1cmbKyo
Common name/Synonyms
Strain types mutant
Background strain
Institution Educational Development Center, Kyoto University of Advanced Science
Depositor Katsuhiko Itoh
Conditions of distribution Users of this strain should cite the article designated by the depositor (Ref. 1) upon publication of the research results. contact us
Animal Health Report
Strain description

APG-1 KO mice are knockout mice of Heat shock 70kDa protein 4-like (Hspa4l, also called APG-1), a member of Hsp110 family.

  1. Itoh K, Kondoh G, Miyachi H, Sugai M, Kaneko Y, Kitano S, Watanabe H, Maeda R, Imura A, Liu Y, Ito C, Itohara S, Toshimori K, and Fujita J. (2019) Dephosphorylation of protamine 2 at serine 56 is crucial for murine sperm maturation in vivo. Sci Signal 12(574):. [PMID:30914484]
Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Hspa4l
Gene name heat shock 70kDa protein 4-like
Genotyping information