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Strain Detail: Tomm5 KO mice

Strain information
Resource No. nbio347
Strain name Tomm5 KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Mice in which the Tomm5 gene was knocked out by genome editing (CRISPR/Cas9). In this strain, part of the first exon was deleted by setting gRNA in exon 1. The product of the Tomm5 gene is present in the mitochondria and contributes to protein transport and has also been implicated in pulmonary fibrosis. This strain is useful for studying mitochondrial protein transport and pulmonary fibrosis.

Resource information
Cryopreserved sperm In-house Genotype Heterozygous
Medium Fertiup
From other institutions Genotype
Cryopreserved embryo In-house Mating System Heterozyous x B6NCr Slc
Genotype Heterozygous or wild
Medium EFS40
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Tomm5
Gene name translocase of outer mitochondrial membrane 5
Genotyping information