HOME > mice > Derlin-1 KO mice
Strain Detail: Derlin-1 KO mice
| Strain information |
| Resource No. |
nbio234 |
| Strain name |
Derlin-1 KO |
| Strain Nomenclature |
C57BL/6J-Derl1tmNCVC |
| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
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| Institution |
Department of Molecular Pathogenesis, National Cerebral and Cardiovascular Center Research Institute |
| Developer |
Toshiyuki Miyata |
| Depositor |
Toshiyuki Miyata (Contact person: Koichi Kokame) |
| Conditions of distribution |
In publishing the research results obtained by use of the biological resource, a citation of the following literature (ref. 1) designated by the depositor is requested. It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
Derlin-1 KO mice are knockout mice for the Derl1 gene. This strain is embryonic lethal at 7 - 8 days of embryonic age. Derlin-1 is an endoplasmic reticulum membrane protein and a member of the Derlin family. |
| Reference(s) |
- Eura Y, Yanamoto H, Arai Y, Okuda T, Miyata T, and Kokame K. (2012) Derlin-1 deficiency is embryonic lethal, Derlin-3 deficiency appears normal, and Herp deficiency is intolerant to glucose load and ischemia in mice. PLoS One 7(3):e34298. [PMID:22479592]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
FERTIUP |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
|
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Derl1 |
| Gene name |
derlin 1 |
| Genotyping information |
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