HOME > mice > FAT-CDO mice
Strain Detail
Strain information | |||
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Resource No. | nbio047 | ||
Strain name | FAT-CDO | ||
Strain Nomenclature | |||
Common name/Synonyms | aP2-CDO mice |
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Strain types | mutant | ||
Background strain | |||
Institution | Division of basic nutrition, National Institute of Health and Nutrition | ||
Developer | |||
Depositor | Nobuyo Kasaoka |
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Conditions of distribution | It's necessary to obtain depositor's consent on use of biological resources. : contact us | ||
Animal Health Report | |||
Strain description |
FAT-CDO mice are transgenic mice overexpressing specifically rat cysteine dioxygenase (CDO) in fat tissue. CDO, a rate-limiting enzyme of taurine synthesis, is expected to promote taurine synthesis in fat tissue. Transgene is designed including aP2 promoter. This strain overexpresses 2-3 times CDO in fat tissue compared with normal mice. This strain are available for research of metabolic syndolome or relationship between taurine and obesity. |
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References | |
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Resource information | |||
Cryopreserved sperm | In-house | Genotype | |
Medium | FERTIUP | ||
From other institutions | Genotype | ||
Medium | |||
Cryopreserved embryo | In-house | Mating System | |
Genotype | |||
Medium | EFS40 | ||
From other institutions | Mating System | ||
Genotype | |||
Medium | |||
Strain status / Availability | Cryopreserved sperm | Within 1 month | |
Cryopreserved embryo | Within 1 month | ||
Live mouse |
Approx. 2 months | ||
Gene information | |||
Mutation types | transgenic | ||
Gene symbol | Cdo | ||
Gene name | Cysteine dioxygenase | ||
Genotyping information |