HOME > mice > FAT-CDO mice
Strain Detail
| Strain information | |||
|---|---|---|---|
| Resource No. | nbio047 | ||
| Strain name | FAT-CDO | ||
| Strain Nomenclature | |||
| Common name/Synonyms | aP2-CDO mice |
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| Strain types | mutant | ||
| Background strain | |||
| Institution | Division of basic nutrition, National Institute of Health and Nutrition | ||
| Developer | |||
| Depositor | Nobuyo Kasaoka |
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| Conditions of distribution | It's necessary to obtain depositor's consent on use of biological resources. : contact us | ||
| Animal Health Report | |||
| Strain description |
FAT-CDO mice are transgenic mice overexpressing specifically rat cysteine dioxygenase (CDO) in fat tissue. CDO, a rate-limiting enzyme of taurine synthesis, is expected to promote taurine synthesis in fat tissue. Transgene is designed including aP2 promoter. This strain overexpresses 2-3 times CDO in fat tissue compared with normal mice. This strain are available for research of metabolic syndolome or relationship between taurine and obesity. |
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| References | |
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| Resource information | |||
| Cryopreserved sperm | In-house | Genotype | |
| Medium | FERTIUP | ||
| From other institutions | Genotype | ||
| Medium | |||
| Cryopreserved embryo | In-house | Mating System | |
| Genotype | |||
| Medium | EFS40 | ||
| From other institutions | Mating System | ||
| Genotype | |||
| Medium | |||
| Strain status / Availability | Cryopreserved sperm | Within 1 month | |
| Cryopreserved embryo | Within 1 month | ||
| Live mouse |
Approx. 2 months | ||
| Gene information | |||
| Mutation types | transgenic | ||
| Gene symbol | Cdo | ||
| Gene name | Cysteine dioxygenase | ||
| Genotyping information | |||