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Strain Detail: Eif2b5-KO mice

Strain information
Resource No. nbio420
Strain name Eif2b5-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Mice in which Eif2b5, one of the causative genes of progressive leukoencephalopathy, was knocked out by genome editing. This strain was created by setting gRNA at two locations in the Eif2b5 gene and deleting Exons 3 to 7. This strain may be useful as a model of progressive leukoencephalopathy.

Resource information
Cryopreserved sperm In-house Genotype Heterozygous
Medium Fertiup
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Eif2b5
Gene name eukaryotic translation initiation factor 2B, subunit 5 epsilon
Genotyping information