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Strain Detail: C57BL/6J(V2K) mice

Strain information
Resource No. nbio314
Strain name C57BL/6J(V2K)
Strain Nomenclature Trpv2-cKO
Common name/Synonyms V2K
Strain types mutant
Background strain C57BL/6J
Institution National Cerebral and Cardiovascular Center
Developer Yuko Iwata
Depositor Yuko Iwata
Conditions of distribution Only for collaboration with the depositor: contact us
Animal Health Report
Strain description

Transient receptor potential cation channel (TRP), subfamily V, member 2 (TRPV2) is a Ca2+-permeable TRP channel. Its pathophysiological roles are still unknown. This strain is a conditional knockout mouse homozygous for floxed TRPV2 alleles (TRPV2FL/FL). Crosses of this strain with Cre mice produce TRPV2-knockout mice.

Resource information
Cryopreserved sperm In-house Genotype V2(fl/fl) 
From other institutions Genotype
Cryopreserved embryo In-house Mating System IVF
Genotype heterozygous for V2K
Medium EFS40
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types conditional KO
Gene symbol Trpv2
Gene name transient receptor potential cation channel, subfamily V, member 2
Genotyping information