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Strain Detail

Strain information
Resource No. nbio017
Strain name AK
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6NCr Slc
Institution National Institutes of Biomedical Innovation, Health and Nutrition (NIBIOHN)(formerly, National Institute of Infectious Diseases)
Developer Junichiro Matsuda
Depositor Junichiro Matsuda
Conditions of distribution without conditions : contact us
Animal Health Report
Strain description

GM1-gangliosidosis is classified three forms : infantile, juvenile and adult, according to the age of onset or clinical manifestation. Each clinical form has a human β-Gal gene mutation. GalA mice express mutant human β-Gal I51T found in adult form. AK mice were produced by introducing human β-Gal I51T gene into β-Gal KO (BKO) mice.

References
Resource information
Cryopreserved sperm In-house Genotype Tg/+, β-Gal (+/-)
Medium FERTIUP
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype Tg/+, β-Gal (+/-), β-Gal (-/-)
Medium EFS40
From other institutions Mating System
Genotype
Medium
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live mouse
Approx. 2 months
Gene information
Mutation types transgenic + knockout
Gene symbol Glb1
Gene name galactosidase, beta 1
Genotyping information