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Strain Detail: H-PGDS-KO mice

Strain information
Resource No. nbio423
Strain name H-PGDS-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6J
Institution Center for Supporting Pharmaceutical Education, Daiichi University of Pharmacy
Developer Yoshihiro Urade
Depositor Yoshihiro Urade
Conditions of distribution The user must cite the reference (Ref. 1) provided by the depositors when publishing the research results. contact us
Animal Health Report
Strain description

Hematopoietic PGD synthase (HPGDS)-deficient mice (mice with exon 2 of HPGDS replaced with a neomycin-resistant gene).

  1. Mohri I, Taniike M, Taniguchi H, Kanekiyo T, Aritake K, Inui T, Fukumoto N, Eguchi N, Kushi A, Sasai H, Kanaoka Y, Ozono K, Narumiya S, Suzuki K, and Urade Y. (2006) Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher. J Neurosci 26(16):4383-93. [PMID:16624958]
Resource information
Cryopreserved sperm In-house Genotype homozygous
Medium Fertiup
From other institutions Genotype
Cryopreserved embryo In-house Mating System homozygous sperm x C57BL/6J Jcl
Genotype heterozygous
Medium EFS40
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Hpgds (H-PGDS)
Gene name hematopoietic prostaglandin D synthase
Genotyping information