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Strain Detail: H-PGDS-KO mice
| Strain information |
| Resource No. |
nbio423 |
| Strain name |
H-PGDS-KO |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
C57BL/6J |
| Institution |
Center for Supporting Pharmaceutical Education, Daiichi University of Pharmacy |
| Developer |
Yoshihiro Urade |
| Depositor |
Yoshihiro Urade |
| Conditions of distribution |
The user must cite the reference (Ref. 1) provided by the depositors when publishing the research results. contact us |
| Animal Health Report |
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| Strain description |
Hematopoietic PGD synthase (HPGDS)-deficient mice (mice with exon 2 of HPGDS replaced with a neomycin-resistant gene). |
| Reference(s) |
- Mohri I, Taniike M, Taniguchi H, Kanekiyo T, Aritake K, Inui T, Fukumoto N, Eguchi N, Kushi A, Sasai H, Kanaoka Y, Ozono K, Narumiya S, Suzuki K, and Urade Y. (2006) Prostaglandin D2-mediated microglia/astrocyte interaction enhances astrogliosis and demyelination in twitcher. J Neurosci 26(16):4383-93. [PMID:16624958]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
homozygous |
| Medium |
Fertiup |
| From other institutions |
Genotype |
|
| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
homozygous sperm ｘ C57BL/6J Jcl |
| Genotype |
heterozygous |
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Hpgds (H-PGDS) |
| Gene name |
hematopoietic prostaglandin D synthase |
| Genotyping information |
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