HOME > mice > mL1-EGFPm16 mice
Strain Detail: mL1-EGFPm16 mice
| Strain information |
| Resource No. |
nbio160 |
| Strain name |
mL1-EGFPm16 |
| Strain Nomenclature |
|
| Common name/Synonyms |
|
| Strain types |
mutant |
| Background strain |
|
| Institution |
National Center for Global Health and Medicine |
| Developer |
|
| Depositor |
Tadashi Okamura |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
|
| Strain description |
mL1-EGFPm16 mice are transgenic mice to be able to monitor LINE1 dynamics by using EGFP expression as a indicator. This strain is available for assay system of carcinogen. These mice express ORF1 and ORF2 which are mouse L1 elements under the control of their own promoter, and express EGFP when transgene is introduced in genome by retro transposition. This strain has 14 lines. It's possible to supply L1-EGFP mice which express human L1 elements. |
| Reference(s) |
|
| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
|
| Medium |
FERTIUP |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
|
| Genotype |
|
| Medium |
EFS40 |
| From other institutions |
Mating System |
|
| Genotype |
|
| Method |
|
| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
LINE1, EGFP |
| Gene name |
Long interspersed nuclear element 1, enhanced green fluorescent protein |
| Genotyping information |
|
