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Strain Detail

Strain information
Resource No. nbio160
Strain name mL1-EGFPm16
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain
Institution National Center for Global Health and Medicine
Developer
Depositor Tadashi Okamura
Conditions of distribution It's necessary to obtain depositor's consent on use of biological resources. : contact us
Animal Health Report
Strain description

mL1-EGFPm16 mice are transgenic mice to be able to monitor LINE1 dynamics by using EGFP expression as a indicator. This strain is available for assay system of carcinogen. These mice express ORF1 and ORF2 which are mouse L1 elements under the control of their own promoter, and express EGFP when transgene is introduced in genome by retro transposition. This strain has 14 lines. It's possible to supply L1-EGFP mice which express human L1 elements.

References
Resource information
Cryopreserved sperm In-house Genotype
Medium FERTIUP
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype
Medium EFS40
From other institutions Mating System
Genotype
Medium
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live mouse
Approx. 2 months
Gene information
Mutation types transgenic
Gene symbol LINE1, EGFP
Gene name Long interspersed nuclear element 1, enhanced green fluorescent protein
Genotyping information