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Strain Detail: Hsp60 Tg line #017
Strain information | |||
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Resource No. | nbio287 | ||
Strain name | Hsp60 Tg line #017 | ||
Strain Nomenclature | |||
Common name/Synonyms | |||
Strain types | mutant | ||
Background strain | C57BL/6J Jcl | ||
Institution | (1) Department of Pharmacology, National Research Institute for Child Health and Development, (2) UNITECH Co., Ltd. | ||
Developer | Junji Yamauchi (1) and Hisashi Tomaru (2) | ||
Depositor | Junji Yamauchi (1) and Hisashi Tomaru (2) | ||
Conditions of distribution |
Collaboration with the depositor only. In publishing the research results obtained by use of the biological resource, a citation of the following literature and the stipulation of an acknowledgment to depositor are requested. It's necessary to obtain depositor's consent on use of biological resources. : contact us |
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Animal Health Report | |||
Strain description |
The Hsp60 Tg line #017 mice are transgenic mice with overexpression of a HSP60 mutant (D25G) in tissues expressing myelin basic protein (MBP). HSP60, a heat shock protein of ~60 kDa, works as a chaperone to assist protein folding. The HSP60 mutant (D25G) may have some effects on the nervous system of this strain. Two lines (#004 and #017) are available. |
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References |
Resource information | |||
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Cryopreserved sperm | In-house | Genotype | |
Medium | |||
From other institutions | Genotype | ||
Medium | |||
Cryopreserved embryo | In-house | Mating System | |
Genotype | |||
Medium | |||
From other institutions | Mating System | IVF | |
Genotype | Mix of heterozygous and wild-type | ||
Medium | DAP213 | ||
Strain status / Availability | Cryopreserved sperm | ||
Cryopreserved embryo | Within 1 month | ||
Live mouse | Please contact us |
Gene information | |||
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Mutation types | transgenic | ||
Gene symbol | HSPD1 | ||
Gene name | heat shock protein family D (Hsp60) member 1 | ||
Genotyping information |