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Strain Detail: Hsp60 Tg line #017

Strain information
Resource No. nbio287
Strain name Hsp60 Tg line #017
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6J Jcl
Institution (1) Department of Pharmacology, National Research Institute for Child Health and Development, (2) UNITECH Co., Ltd.
Developer Junji Yamauchi (1) and Hisashi Tomaru (2)
Depositor Junji Yamauchi (1) and Hisashi Tomaru (2)
Conditions of distribution

Collaboration with the depositor only. In publishing the research results obtained by use of the biological resource, a citation of the following literature and the stipulation of an acknowledgment to depositor are requested. It's necessary to obtain depositor's consent on use of biological resources. : contact us

Animal Health Report
Strain description

The Hsp60 Tg line #017 mice are transgenic mice with overexpression of a HSP60 mutant (D25G) in tissues expressing myelin basic protein (MBP). HSP60, a heat shock protein of ~60 kDa, works as a chaperone to assist protein folding. The HSP60 mutant (D25G) may have some effects on the nervous system of this strain. Two lines (#004 and #017) are available.

References
Resource information
Cryopreserved sperm In-house Genotype
Medium
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype
Medium
From other institutions Mating System IVF
Genotype Mix of heterozygous and wild-type
Medium DAP213
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo Within 1 month
Live mouse Please contact us
Gene information
Mutation types transgenic
Gene symbol HSPD1
Gene name heat shock protein family D (Hsp60) member 1
Genotyping information