HOME > mice > Lck-Cre mice
Strain Detail: Lck-Cre mice
| Strain information |
| Resource No. |
nbio025 |
| Strain name |
Lck-Cre |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
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| Institution |
Faculty of Medicine, Osaka University |
| Developer |
Junji Takeda |
| Depositor |
Junji Takeda |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
Lck-Cre mice are transgenic mice expressing specifically Cre recombinase in T-cell and used for tissue specific gene disruption. Lck proximal promoter is used to regulate T-cell specific expression. This strain is available for the research of immune system related to T-cell. It's very likely that transgene is inserted into chromosome 7 because of linkage with tyrosinase gene. |
| Reference(s) |
- Takahama Y, Ohishi K, Tokoro Y, Sugawara T, Yoshimura Y, Okabe M, Kinoshita T, and Takeda J. (1998) Functional competence of T cells in the absence of glycosylphosphatidylinositol-anchored proteins caused by T cell-specific disruption of the Pig-α gene. Eur. J. Immunol. 28(7):2159-66. [PMID:9692885]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
FERTIUP |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
