HOME > mice > Lck-Cre mice
Strain Detail
Strain information | |||
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Resource No. | nbio025 | ||
Strain name | Lck-Cre | ||
Strain Nomenclature | |||
Common name/Synonyms | |||
Strain types | mutant | ||
Background strain | |||
Institution | Faculty of Medicine, Osaka University | ||
Developer | Junji Takeda |
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Depositor | Junji Takeda |
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Conditions of distribution | It's necessary to obtain depositor's consent on use of biological resources. : contact us | ||
Animal Health Report | |||
Strain description |
Lck-Cre mice are transgenic mice expressing specifically Cre recombinase in T-cell and used for tissue specific gene disruption. Lck proximal promoter is used to regulate T-cell specific expression. This strain is available for the research of immune system related to T-cell. It's very likely that transgene is inserted into chromosome 7 because of linkage with tyrosinase gene. |
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References |
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Resource information | |||
Cryopreserved sperm | In-house | Genotype | |
Medium | FERTIUP | ||
From other institutions | Genotype | ||
Medium | |||
Cryopreserved embryo | In-house | Mating System | |
Genotype | |||
Medium | EFS40 | ||
From other institutions | Mating System | ||
Genotype | |||
Medium | |||
Strain status / Availability | Cryopreserved sperm | Within 1 month | |
Cryopreserved embryo | Within 1 month | ||
Live mouse |
Approx. 2 months | ||
Gene information | |||
Mutation types | transgenic | ||
Gene symbol | Lck, Cre | ||
Gene name | Lymphocyte-specific protein tyrosine kinase, Cre recombinase | ||
Genotyping information | Genotyping protocol for LCK-Cre mice (pdf). |