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Strain Detail: Trp53 KO mice

Strain information
Resource No. nbio348
Strain name Trp53 KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

A mouse strain in which Trp53 is knocked out by genome editing (CRISPR/Cas9). Guide RNAs were set at two locations (Exons 4 and 5) in the Trp53 gene, and a part of the coding sequence was deleted. The strain is expected to be used as a model for oncology and pulmonary fibrosis.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Trp53
Gene name transformation related protein 53
Genotyping information