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Strain Detail: Kuro

Strain information
Resource No. nbio289
Strain name Kuro
Strain Nomenclature
Common name/Synonyms
Strain types spontaneous mutant
Background strain
Institution Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu Univesrsity
Developer Hiroshi Tekemori
Depositor Hiroshi Tekemori
Conditions of distribution

In 2015-2017,only for collaboration with the depositor : contact us. In 2018 and later, the source of the mice and an acknowledgment to the depositor have to be included in publications.

Animal Health Report
Strain description Photo of Kuro (right) and HR-1 (left) mice

This strain has dark skin with no hair coat, found in mixed crosses between C57BL/6 and C3H strains. Mice of C57BL/6J strain, one of the parental strains, have black hair but their skin has light pink and gray to black areas. Mice of C3H strain, another parental strain, have agouti hairs and the skin has dark and light areas (Ref. 1). Different from both parental strains, the Kuro mice have very dark skin in a whole body, including the surface of the tongue. The Kuro mice are sterile with smaller body size. Deficient hair elongation is due to the production of too many hair roots and loss of the hair root polarity. Genes responsible for these phenotypes are unknown. Heterozygous Kuro mice are easily differentiated from the homozygous Kuro mice because the heterozygous Kuro mice have sparse hair coats.

References
    Resource information
    Cryopreserved sperm In-house Genotype Heterozygous and homozygous
    Medium FERTIUP
    From other institutions Genotype
    Medium
    Cryopreserved embryo In-house Mating System IVF
    Genotype Homozygous, and mix of heterozygous and wild-type
    Medium EFS40
    From other institutions Mating System
    Genotype
    Method
    Strain status / Availability Cryopreserved sperm Within 1 month
    Cryopreserved embryo Within 1 month
    Live animals Approx. 2 months
    Gene information
    Mutation types spontaneous mutation
    Gene symbol unknown
    Gene name unknown
    Genotyping information Homozygous mice have no hair coat. Heterozygous mice have sparse hair coats.