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Strain Detail: Kuro mice
| Strain information | |
|---|---|
| Resource No. | nbio289 |
| Strain name | Kuro |
| Strain Nomenclature | |
| Common name/Synonyms | |
| Strain types | spontaneous mutant |
| Background strain | |
| Institution | Department of Chemistry and Biomolecular Science, Faculty of Engineering, Gifu Univesrsity |
| Developer | Hiroshi Tekemori |
| Depositor | Hiroshi Tekemori |
| Conditions of distribution | In 2015-2017，only for collaboration with the depositor. contact us. In 2018 and later, the source of the mice and an acknowledgment to the depositor have to be included in publications. |
| Animal Health Report | |
| Strain description |  This strain has dark skin with no hair coat, found in mixed crosses between C57BL/6 and C3H strains. Mice of C57BL/6J strain, one of the parental strains, have black hair but their skin has light pink and gray to black areas. Mice of C3H strain, another parental strain, have agouti hairs and the skin has dark and light areas (Ref. 1). Different from both parental strains, the Kuro mice have very dark skin in a whole body, including the surface of the tongue. The Kuro mice are sterile with smaller body size. Deficient hair elongation is due to the production of too many hair roots and loss of the hair root polarity. Genes responsible for these phenotypes are unknown. Heterozygous Kuro mice are easily differentiated from the homozygous Kuro mice because the heterozygous Kuro mice have sparse hair coats. |
| Reference(s) |
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| Resource information | |||
|---|---|---|---|
| Cryopreserved sperm | In-house | Genotype | Heterozygous and homozygous |
| Medium | FERTIUP | ||
| From other institutions | Genotype | ||
| Medium | |||
| Cryopreserved embryo | In-house | Mating System | IVF |
| Genotype | Homozygous, and mix of heterozygous and wild-type | ||
| Medium | EFS40 | ||
| From other institutions | Mating System | ||
| Genotype | |||
| Method | |||
| Strain status / Availability | Cryopreserved sperm | Within 1 month | |
| Cryopreserved embryo | Within 1 month | ||
| Live animals | Approx. 2 months | ||
| Gene information | |
|---|---|
| Mutation types | spontaneous mutation |
| Gene symbol | unknown |
| Gene name | unknown |
| Genotyping information | Homozygous mice have no hair coat. Heterozygous mice have sparse hair coats. |