HOME > mice > Cysltr2-KO mice

Strain Detail: Cysltr2-KO mice

Strain information
Resource No. nbio368
Strain name Cysltr2-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Knockout mice of one of the leukotriene receptors, Cysltr2 (cystinyl leukotriene receptor 2). Guide RNAs were set at two locations in the UTR region of the Cysltr2 gene, and the entire coding sequence was deleted by genome editing. This strain is expected to be used as a model for pulmonary fibrosis and bronchial asthma.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Cysltr2
Gene name cysteinyl leukotriene receptor 2
Genotyping information