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Strain Detail: Cysltr2-KO mice
| Strain information |
| Resource No. |
nbio368 |
| Strain name |
Cysltr2-KO |
| Strain Nomenclature |
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| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
C57BL/6N |
| Institution |
Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition |
| Developer |
Osamu Suzuki |
| Depositor |
Osamu Suzuki |
| Conditions of distribution |
Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
Knockout mice of one of the leukotriene receptors, Cysltr2 (cystinyl leukotriene receptor 2).
Guide RNAs were set at two locations in the UTR region of the Cysltr2 gene, and the entire coding sequence was deleted by genome editing.
This strain is expected to be used as a model for pulmonary fibrosis and bronchial asthma. |
| Reference(s) |
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
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| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
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| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Cysltr2 |
| Gene name |
cysteinyl leukotriene receptor 2 |
| Genotyping information |
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