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Strain Detail: C57BL/6J(V2D) mice

Strain information
Resource No. nbio313
Strain name C57BL/6J(V2D)
Strain Nomenclature
Common name/Synonyms V2D
Strain types mutant
Background strain C57BL/6J
Institution National Cerebral and Cardiovascular Center
Developer Yuko Iwata
Depositor Yuko Iwata
Conditions of distribution Only for collaboration with the depositor: contact us
Animal Health Report
Strain description

Transient receptor potential cation channel (TRP), subfamily V, member 2 (TRPV2) is a Ca2+-permeable TRP channel. Its pathophysiological roles are still unknown. This strain is a mouse line heterozygous for floxed and wild-type Trpv2 alleles. The floxed alleles, derived from V2K, has been silenced (TRPV2del) by crossing mice with CMV-driven Cre, but no CMV-Cre is left in the strain. Crossing between males and females of this strain produces TRPV2 knock-out mice.

Resource information
Cryopreserved sperm In-house Genotype V2(Δ/Δ)及びV2(Δ/W)
From other institutions Genotype
Cryopreserved embryo In-house Mating System IVF
Genotype heterozygous and wild-type for V2(Δ)
Medium EFS40
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Trpv2
Gene name transient receptor potential cation channel, subfamily V, member 2
Genotyping information