HOME > mice > Conditional KI (Bim) mice
Strain Detail: Conditional KI (Bim) mice
Strain information |
Resource No. |
nbio346 |
Strain name |
Conditional KI (Bim) |
Strain Nomenclature |
|
Common name/Synonyms |
|
Strain types |
mutant |
Background strain |
C57BL/6J |
Institution |
(1) Department of Pharmacology, National Research Institute for Child Health and Development, and (2) UNITECH Co., Ltd. |
Developer |
Junji Yamauchi (1) and Hisashi Tomaru (2) |
Depositor |
Junji Yamauchi (1) and Hisashi Tomaru (2) |
Conditions of distribution |
Limited to collaborative research with depositors. Users shall cite references specified by the depositor when publishing research results. Users shall give an acknowledgment to the depositor when publishing the research results. Users shall obtain the consent of the depositor in advance. contact us |
Animal Health Report |
|
Strain description |
Bim, a.k.a. Bcl2l11 (BCL2-like 11 (apoptosis facilitator)), is one of BCL-2 family members and acts as
an anti- or pro-apoptotic regulator. The strain is a conditional knockin mouse strain in which Bim expresses in tissues with Cre expression. The integrated transgene has a stop cassette surrounded by loxP between the CAG promoter and the Bim cDNA. The stop cassette is removed in the tissues where Cre is expressed, and the Bim becomes expressed. The strain is useful for BIM research. |
Reference(s) |
|
Resource information |
Cryopreserved sperm |
In-house |
Genotype |
heterozygous |
Medium |
|
From other institutions |
Genotype |
|
Medium |
|
Cryopreserved embryo |
In-house |
Mating System |
|
Genotype |
heterozygous / wild-type |
Medium |
|
From other institutions |
Mating System |
|
Genotype |
|
Method |
|
Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
Cryopreserved embryo |
Within 1 month |
Live animals |
Approx. 2 months |
Gene information |
Mutation types |
Conditional KI |
Gene symbol |
Bim (a.k.a., Bcl2l11, 1500006F24Rik, Bod) |
Gene name |
BCL2-like 11 (apoptosis facilitator) |
Genotyping information |
|