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Strain Detail: Conditional KO(CD69) mice

Strain information
Resource No. nbio315
Strain name Conditional KO(CD69)
Strain Nomenclature
Common name/Synonyms CD69 cKO
Strain types mutant
Background strain C57BL/6J
Institution (1) Department of Pharmacology, National Research Institute for Child Health and Development, (2) UNITECH Co., Ltd.
Developer Junji Yamauchi (1) and Hisashi Tomaru (2)
Depositor Junji Yamauchi (1) and Hisashi Tomaru (2)
Conditions of distribution

Collaboration with the depositor only. In publishing the research results obtained by use of the biological resource, a citation of the following literature and the stipulation of an acknowledgment to depositor are requested. It's necessary to obtain depositor's consent on use of biological resources. : contact us

Animal Health Report
Strain description

CD69 proteins are expressed as an cell-surface protein in activated lymphocytes and macropahges, as well as some other blood cells. The protein is thought to be involved in the autoimmune and allergic diseases.

This strain of mice has a floxed exon in Cd69 gene. The Cd69 gene can be silenced (knocked out) by the mating with Cre mice. The strain can be used as a research tool for functional studies of Cd69 in a wide variety of immune diseases.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types conditional KO
Gene symbol Cd69
Gene name CD69 antigen
Genotyping information