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Strain Detail: Dglucy-KO mice
| Strain information |
| Resource No. |
nbio365 |
| Strain name |
Dglucy-KO |
| Strain Nomenclature |
RIKEN cDNA 9030617O03 KO (-/-) |
| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
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| Institution |
Department of Cardiovascular Medicine, Department of Nephrology, Graduate School of Medical Science, Kyoto Prefectural University of Medicine |
| Developer |
Satoaki Matoba |
| Depositor |
Satoaki Matoba |
| Conditions of distribution |
without conditions: contact us |
| Animal Health Report |
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| Strain description |
D-glutamate cyclase (Dglucy, a.k.a.,9030617O03Rik) is an enzyme which converts D-glutamate to 5-oxo-D-proline. The Dglucy-KO mice are knockout mice for the Dglucy gene. The mice are useful for analyzing D-amino acid functions in mammals. Mice for conditional Dglucy KO mouse production (Dglucy cKO mice) are also available. |
| Reference(s) |
- Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, Okawa Y, Mita Y, Kaimoto S, Uchihashi M, Fukai K, Ono K, Tateishi S, Hato D, Yamanaka R, Honda S, Fushimura Y, Iwai-Kanai E, Ishihara N, Mita M, Homma H, and Matoba S. (2017) D-Glutamate is metabolized in the heart mitochondria. Sci Rep 7: 43911. [PMID:28266638]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
Heterozygous |
| Medium |
Fertiup |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
Mix of heterozygotes and wild-types |
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout |
| Gene symbol |
Dglucy, a.k.a., 9030617O03Rik |
| Gene name |
D-glutamate cyclase |
| Genotyping information |
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