HOME > mice > L-PGDS TG #B-7 mice
Strain Detail: L-PGDS TG #B-7 mice
| Strain information |
| Resource No. |
nbio389 |
| Strain name |
L-PGDS TG #B-7 |
| Strain Nomenclature |
Human Lipocalin-type Prostaglandin D Synthase transgenic mice (Subline: B-7) |
| Common name/Synonyms |
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| Strain types |
mutant |
| Background strain |
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| Institution |
Center for Supporting Pharmaceutical Education, Daiichi University of Pharmacy |
| Developer |
Yoshihiro Urade |
| Depositor |
Yoshihiro Urade |
| Conditions of distribution |
Users shall cite references specified by the depositor when publishing research results.contact us |
| Animal Health Report |
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| Strain description |
Transgenic mice that systemically express human lipocalin-type prostaglandin synthase (L-PGDS). Three sublines are available (#B-7, #B-17, #B20). The mice are useful for studying the function of L-PGDS, which is abundant in the cerebrospinal fluid of mammals. |
| Reference(s) |
- Pinzar E, Kanaoka Y, Inui T, Eguchi N, Urade Y, and Hayaishi O. (2000) Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep. Proc Natl Acad Sci U S A 97(9):4903-7. [PMID:10781097]
- Fujitani Y, Kanaoka Y, Aritake K, Uodome N, Okazaki-Hatake K, and Urade Y. (2002) Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. J Immunol 168(1):443-9. [PMID:11751991]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
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| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
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| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
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| Cryopreserved embryo |
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| Live animals |
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| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
Ptgds |
| Gene name |
prostaglandin D2 synthase (brain), Lipocalin-type Prostaglandin D Synthase |
| Genotyping information |
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