HOME > mice > L-PGDS TG #B-7 mice

Strain Detail: L-PGDS TG #B-7 mice

Strain information
Resource No. nbio389
Strain name L-PGDS TG #B-7
Strain Nomenclature Human Lipocalin-type Prostaglandin D Synthase transgenic mice (Subline: B-7)
Common name/Synonyms
Strain types mutant
Background strain
Institution Center for Supporting Pharmaceutical Education, Daiichi University of Pharmacy
Developer Yoshihiro Urade
Depositor Yoshihiro Urade
Conditions of distribution Users shall cite references specified by the depositor when publishing research results.contact us
Animal Health Report
Strain description

Transgenic mice that systemically express human lipocalin-type prostaglandin synthase (L-PGDS). Three sublines are available (#B-7, #B-17, #B20). The mice are useful for studying the function of L-PGDS, which is abundant in the cerebrospinal fluid of mammals.

  1. Pinzar E, Kanaoka Y, Inui T, Eguchi N, Urade Y, and Hayaishi O. (2000) Prostaglandin D synthase gene is involved in the regulation of non-rapid eye movement sleep. Proc Natl Acad Sci U S A 97(9):4903-7. [PMID:10781097]
  2. Fujitani Y, Kanaoka Y, Aritake K, Uodome N, Okazaki-Hatake K, and Urade Y. (2002) Pronounced eosinophilic lung inflammation and Th2 cytokine release in human lipocalin-type prostaglandin D synthase transgenic mice. J Immunol 168(1):443-9. [PMID:11751991]
Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types transgenic
Gene symbol Ptgds
Gene name prostaglandin D2 synthase (brain), Lipocalin-type Prostaglandin D Synthase
Genotyping information