HOME > mice > CD72flox mice

Strain Detail: CD72flox mice

Strain information
Resource No. nbio343
Strain name CD72flox
Strain Nomenclature
Common name/Synonyms CD72 knockout
Strain types mutant
Background strain C57BL/6
Institution Immunology Department, Medical Research Institute, Tokyo Medical and Dental University
Developer Takeshi Tsubata
Depositor Takeshi Tsubata
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Mouse strain in which exon of CD72 gene is floxed (sandwiched by two loxP sites). By crossing with Cre mice, we can produce mice in which the CD72 gene has been knocked out. CD72 knockout mice develop a relatively severe SLE-like autoimmune disease.

Reference(s)
Resource information
Cryopreserved sperm In-house Genotype
Medium
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype
Medium
From other institutions Mating System
Genotype
Method
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types Conditional KO
Gene symbol Cd72
Gene name CD72 antigen, Ly-19, Ly-32, Lyb-2, Ly-m19
Genotyping information
/html>