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Strain Detail: CD72flox mice
Strain information |
Resource No. |
nbio343 |
Strain name |
CD72flox |
Strain Nomenclature |
|
Common name/Synonyms |
CD72 knockout |
Strain types |
mutant |
Background strain |
C57BL/6 |
Institution |
Immunology Department, Medical Research Institute, Tokyo Medical and Dental University |
Developer |
Takeshi Tsubata |
Depositor |
Takeshi Tsubata |
Conditions of distribution |
Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us |
Animal Health Report |
|
Strain description |
Mouse strain in which exon of CD72 gene is floxed (sandwiched by two loxP sites). By crossing with Cre mice, we can produce mice in which the CD72 gene has been knocked out. CD72 knockout mice develop a relatively severe SLE-like autoimmune disease. |
Reference(s) |
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Resource information |
Cryopreserved sperm |
In-house |
Genotype |
|
Medium |
|
From other institutions |
Genotype |
|
Medium |
|
Cryopreserved embryo |
In-house |
Mating System |
|
Genotype |
|
Medium |
|
From other institutions |
Mating System |
|
Genotype |
|
Method |
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Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
Cryopreserved embryo |
Within 1 month |
Live animals |
Approx. 2 months |
Gene information |
Mutation types |
Conditional KO |
Gene symbol |
Cd72 |
Gene name |
CD72 antigen, Ly-19, Ly-32, Lyb-2, Ly-m19 |
Genotyping information |
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