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Strain Detail: Hck-KO mice

Strain information
Resource No. nbio384
Strain name Hck-KO
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6N
Institution Laboratory of Animal Models for Human Diseases, National Institutes of Biomedical Innovation, Health and Nutrition
Developer Osamu Suzuki
Depositor Osamu Suzuki
Conditions of distribution Collaboration with the depositor only. It's necessary to obtain depositor's consent on use of biological resources. contact us
Animal Health Report
Strain description

Knockout mice of hemopoietic cell kinase (HCK), a protein tyrosine kinase belonging to the Src family. The Hck gene was created by setting gRNAs at two locations, Exon 2 and Exon 6, and deleting the gap between them by genome editing. It is expected to be used as a model for myeloproliferative disorders and pulmonary fibrosis.

Resource information
Cryopreserved sperm In-house Genotype
From other institutions Genotype
Cryopreserved embryo In-house Mating System
From other institutions Mating System
Strain status / Availability Cryopreserved sperm
Cryopreserved embryo
Live animals
Gene information
Mutation types knockout
Gene symbol Hck
Gene name hemopoietic cell kinase
Genotyping information