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Strain Detail: B6/lprC1scg mice

Strain information
Resource No. nbio392
Strain name B6/lprC1scg
Strain Nomenclature
Common name/Synonyms HamanoA
Strain types congenic
Background strain C57BL/6-lpr
Institution Tokyo Metropolitan Institute of Gerontology
Developer Yoshitomo Hamano
Depositor Yoshitomo Hamano
Conditions of distribution The user must cite the reference (Ref. 1) provided by the depositor when publishing the research results. The consent of the depositor for the use of biological resources is required. contact us
Animal Health Report
Strain description

Congenic mice with spontaneous lupus nephritis, vasculitis, and MPO-ANCA production. A portion of chromosome 1 from SCG/Kj mice was introduced into B6/lpr by backcrossing.

Reference(s)
  1. Hamano Y, Ito F, Suzuki O, Koura M, Matsuoka S, Kobayashi T, Sugitani Y, Wali N, Koyanagi A, Hino O, Suzuki S, Sugamata R, Yoshizawa H, Yumura W, Maruyama N, Kameoka Y, Noda Y, Hasegawa Y, Arai T, and Suzuki K. (2019) Vasculitis and crescentic glomerulonephritis in a newly established congenic mouse strain derived from ANCA-associated vasculitis-prone SCG/Kj mice. Autoimmunity 52(5-6):208-219. [PMID:31476889]
Resource information
Cryopreserved sperm In-house Genotype Homozygous
Medium Fertiup
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System Homozygous x Homozygous
Genotype Homozygous
Medium EFS40
From other institutions Mating System
Genotype
Method
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types congenic
Gene symbol C1scg
Gene name Part of the chomosome 1 of the SCG/Kj strain
Genotyping information