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Strain Detail: Conditional KO (Cytohesin-2) mice

Strain information
Resource No. nbio311
Strain name Conditional KO (Cytohesin-2)
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain C57BL/6J Jcl
Institution (1) Department of Pharmacology, National Research Institute for Child Health and Development, (2) UNITECH Co., Ltd.
Developer Junji Yamauchi (1) and Hisashi Tomaru (2)
Depositor Junji Yamauchi (1) and Hisashi Tomaru (2)
Conditions of distribution

Collaboration with the depositor only. In publishing the research results obtained by use of the biological resource, a citation of the following literature and the stipulation of an acknowledgment to depositor are requested. It's necessary to obtain depositor's consent on use of biological resources. : contact us

Animal Health Report
Strain description

This strain of mice has a floxed exon in Cyth2 gene. The Cyth2 gene can be silenced (knocked out) by the mating with Cre mice.

Cytohesin-2 acts as guanine nucleotide exchange factor (GEF) and is involved in the intracellular signal transduction pathway regulated by G proteins.

Resource information
Cryopreserved sperm In-house Genotype Homozygous
From other institutions Genotype
Cryopreserved embryo In-house Mating System IVF
Genotype Heterozygous
Medium EFS40
From other institutions Mating System
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types Conditional KO (Cytohesin-2)
Gene symbol Cyth2
Gene name Cytohesin-2
Genotyping information