HOME > mice > Conditional KO (Cytohesin-2) mice
Strain Detail: Conditional KO (Cytohesin-2) mice
| Strain information | |
|---|---|
| Resource No. | nbio311 |
| Strain name | Conditional KO (Cytohesin-2) |
| Strain Nomenclature | |
| Common name/Synonyms | |
| Strain types | mutant |
| Background strain | C57BL/6J Jcl |
| Institution | (1) Department of Pharmacology, National Research Institute for Child Health and Development, (2) UNITECH Co., Ltd. |
| Developer | Junji Yamauchi (1) and Hisashi Tomaru (2) |
| Depositor | Junji Yamauchi (1) and Hisashi Tomaru (2) |
| Conditions of distribution | Collaboration with the depositor only. In publishing the research results obtained by use of the biological resource, a citation of the following literature and the stipulation of an acknowledgment to depositor are requested. It's necessary to obtain depositor's consent on use of biological resources. : contact us |
| Animal Health Report | |
| Strain description | This strain of mice has a floxed exon in Cyth2 gene. The Cyth2 gene can be silenced (knocked out) by the mating with Cre mice. Cytohesin-2 acts as guanine nucleotide exchange factor (GEF) and is involved in the intracellular signal transduction pathway regulated by G proteins. |
| Reference(s) | |
| Resource information | |||
|---|---|---|---|
| Cryopreserved sperm | In-house | Genotype | Homozygous |
| Medium | FERTIUP | ||
| From other institutions | Genotype | ||
| Medium | |||
| Cryopreserved embryo | In-house | Mating System | IVF |
| Genotype | Heterozygous | ||
| Medium | EFS40 | ||
| From other institutions | Mating System | ||
| Genotype | |||
| Method | |||
| Strain status / Availability | Cryopreserved sperm | Within 1 month | |
| Cryopreserved embryo | Within 1 month | ||
| Live animals | Approx. 2 months | ||
| Gene information | |
|---|---|
| Mutation types | Conditional KO (Cytohesin-2) |
| Gene symbol | Cyth2 |
| Gene name | Cytohesin-2 |
| Genotyping information | |