HOME > mice > Delta NHE1-TG mice
Strain Detail
Strain information | |||
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Resource No. | nbio231 | ||
Strain name | Delta NHE1-TG | ||
Strain Nomenclature | |||
Common name/Synonyms | ΔNHE1-TG | ||
Strain types | mutant | ||
Background strain | |||
Institution | Department of Molecular Physiology, National Cardiovascular Center Research Institute | ||
Developer | Shigeo Wakabayashi | ||
Depositor | Shigeo Wakabayashi | ||
Conditions of distribution | It's necessary to obtain depositor's consent on use of biological resources. Only for collaboration with the depositor : contact us |
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Animal Health Report | |||
Strain description |
This strain is specifically overexpressing activated NHE1 in myocardia, therefore it's a cardiac hypertrophy and heart failure model triggered by increase of intracellular Na+ concentration by NHE1 activation. NHE1 is a important ion transporter to keep cell homeostasis and a member of Na+/H+ Exchangers (NHE) family. |
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Resource information | |||
Cryopreserved sperm | In-house | Genotype | |
Medium | FERTIUP | ||
From other institutions | Genotype | ||
Medium | |||
Cryopreserved embryo | In-house | Mating System | |
Genotype | |||
Medium | EFS40 | ||
From other institutions | Mating System | ||
Genotype | |||
Medium | |||
Strain status / Availability | Cryopreserved sperm | Within 1 month | |
Cryopreserved embryo | Within 1 month | ||
Live mouse |
Approx. 2 months | ||
Gene information | |||
Mutation types | transgenic | ||
Gene symbol | SLC9A1 | ||
Gene name | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member | ||
Genotyping information |