HOME > mice > LECT2-Tg33 (C57BL/6JJcl) mice

Strain Detail

Strain information
Resource No. nbio181
Strain name LECT2-Tg33 (C57BL/6JJcl)
Strain Nomenclature
Common name/Synonyms
Strain types mutant
Background strain
Institution Department of Chemotherapy and Mycoses, National Institute of Infectious Diseases
Developer Satoshi Yamagoe
Depositor Satoshi Yamagoe
Conditions of distribution It's necessary to obtain depositor's consent on use of biological resources.
Only for collaboration with the depositor : contact us
Animal Health Report
Strain description

Leukocyte cell-derived chemotaxin 2 (LECT2) is a cytokine found as neutrophil chemotactic factor and a 16 kDa protein specifically expressing in liver parenchymal cells. It's considered that LECT2 is related to various disease such as hepatic dysfunction or rheumatoid arthritis. LECT2-Tg mice express mouse LECT2 under the control of CAG promoter in whole body. This strain has two lines, 12 or 33, and each line has different gene background, BALB/cAJcl or C57BL/6JJcl. Therefore, 4 types of LECT2-Tg mice are available. Especially, line 33 is ten to hundred times LECT2 concentration in blood compared with wildtype. This strain is useful for the elucidation of in vivo function of LECT2.

References
Resource information
Cryopreserved sperm In-house Genotype
Medium FERTIUP
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype
Medium EFS40
From other institutions Mating System
Genotype
Medium
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live mouse
Approx. 2 months
Gene information
Mutation types knockout
Gene symbol Lect2
Gene name Leukocyte cell-derived chemotaxin 2
Genotyping information