HOME > mice > L1-EGFP#B5 mice
Strain Detail: L1-EGFP#B5 mice
| Strain information |
| Resource No. |
nbio138 |
| Strain name |
L1-EGFP#B5 |
| Strain Nomenclature |
|
| Common name/Synonyms |
|
| Strain types |
mutant |
| Background strain |
|
| Institution |
National Center for Global Health and Medicine |
| Developer |
|
| Depositor |
Tadashi Okamura |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
|
| Strain description |
L1-EGFP#B5 mice are transgenic mice to be able to monitor LINE1 dynamics by using EGFP expression as a indicator. This strain is available for assay system of carcinogen. These mice express ORF1 and ORF2 which are human L1 elements under the control of their own promoter, and express EGFP when transgene is introduced in genome by retro transposition. This strain has 16 lines. It's possible to supply mL1-EGFP mice which express mouse L1 elements. |
| Reference(s) |
- Okudaira N, Goto M, Yanobu-Takanashi R, Tamura M, An A, Abe Y, Kano S, Hagiwara S, Ishizaka Y, Okamura T. (2011) Involvement of retrotransposition of long interspersed nucleotide element-1 in skin tumorigenesis induced by 7,12-dimethylbenz[a]anthracene and 12-O-tetradecanoylphorbol-13-acetate. Cancer Sci. 102(11):2000-6. [PMID: 21827582]
|
| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
|
| Medium |
FERTIUP |
| From other institutions |
Genotype |
|
| Medium |
|
| Cryopreserved embryo |
In-house |
Mating System |
|
| Genotype |
|
| Medium |
EFS40 |
| From other institutions |
Mating System |
|
| Genotype |
|
| Method |
|
| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
