HOME > mice > Rgs16 knockdown mouse line#53 mice
Strain Detail: Rgs16 knockdown mouse line#53 mice
| Strain information |
| Resource No. |
nbio182 |
| Strain name |
Rgs16 knockdown mouse line#53 |
| Strain Nomenclature |
|
| Common name/Synonyms |
Rgs16 KD-line#53 |
| Strain types |
mutant |
| Background strain |
C57BL/6JJcl |
| Institution |
Kinki University School of Medicine |
| Developer |
Naoto Hayasaka |
| Depositor |
Naoto Hayasaka |
| Conditions of distribution |
In publishing the research results obtained by use of the biological resource, a citation of the following literature (ref. 1) designated by the depositor is requested. It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
Rgs16 knockdown mouse line#53 decreases expression of Rgs16, which is a member of regulators of G protein Signaling (RGS) family. This mouse is transgenic mouse generated to use lentiviral vector expressing Rgs16 mRNA targeted shRNA. This strain shows to change the cycle of locomotor activity rhythms and reduce total activity level, furthermore reduce food anticipatory activity (FAA) in the scheduled feeding. It's considered that this strain is useful model of anomaly of circadian locomotor rhythms. Gene background is C57BL/6JJcl. |
| Reference(s) |
- Hayasaka N, Aoki K, Kinoshita S, Yamaguchi S, Wakefield JK, Tsuji-Kawahara S, Horikawa K, Ikegami H, Wakana S, Murakami T, Ramabhadran R, Miyazawa M, and Shibata S. (2011) Attenuated food anticipatory activity and abnormal circadian locomotor rhythms in Rgs16 knockdown mice. PLoS One 6(3):e17655. [PMID:21408016]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
|
| Medium |
FERTIUP |
| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
|
| Genotype |
|
| Medium |
EFS40 |
| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
transgenic |
| Gene symbol |
Rgs16 |
| Gene name |
Regulator of G-protein signaling 16 |
| Genotyping information |
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