HOME > mice > C57BL/6-TgCasp8tm1DED Tg(EGFP)Kyo mice
Strain Detail: C57BL/6-TgCasp8tm1DED Tg(EGFP)Kyo mice
| Strain information |
| Resource No. |
nbio225 |
| Strain name |
C57BL/6-TgCasp8tm1DED Tg(EGFP)Kyo |
| Strain Nomenclature |
C57BL/6-TgCasp8tm1DED Tg(EGFP)Kyo |
| Common name/Synonyms |
Casp8-KO & EGFP-Tg |
| Strain types |
mutant |
| Background strain |
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| Institution |
Department of Animal Development and Physiology, Kyoto University |
| Developer |
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| Depositor |
Kazuhiro Sakamaki |
| Conditions of distribution |
It's necessary to obtain depositor's consent on use of biological resources. contact us |
| Animal Health Report |
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| Strain description |
This strain was produced by mating between Caspase-8 knockout mouse (ref.1) and EGFP mouse (ref.2). Caspase-8 homozygous knockout mice are embryonic lethal, thus this strain is maintained by using heterozygous mice. |
| Reference(s) |
- Sakamaki K, Inoue T, Asano M, Sudo K, Kazama H, Sakagami J, Sakata S, Ozaki M, Nakamura S, Toyokuni S, Osumi N, Iwakura Y, and Yonehara S. (2002) Ex vivo whole-embryo culture of caspase-8-deficient embryos normalize their aberrant phenotypes in the developing neural tube and heart. Cell Death Differ 9(11):1196-206. [PMID:12404118]
- Okabe M, Ikawa M, Kominami K, Nakanishi T, and Nishimune Y. (1997) 'Green mice' as a source of ubiquitous green cells. FEBS Lett 407(3):313-9. [PMID:9175875]
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| Resource information |
| Cryopreserved sperm |
In-house |
Genotype |
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| Medium |
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| From other institutions |
Genotype |
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| Medium |
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| Cryopreserved embryo |
In-house |
Mating System |
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| Genotype |
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| Medium |
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| From other institutions |
Mating System |
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| Genotype |
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| Method |
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| Strain status / Availability |
Cryopreserved sperm |
Within 1 month |
| Cryopreserved embryo |
Within 1 month |
| Live animals |
Approx. 2 months |
| Gene information |
| Mutation types |
knockout + transgenic |
| Gene symbol |
Casp8, EGFP |
| Gene name |
Caspase 8, Enhanced Green Fluorescent Protein |
| Genotyping information |
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