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Strain Detail: C57BL/6-Tg(Mx-Cre)Kyo mice

Strain information
Resource No. nbio227
Strain name C57BL/6-Tg(Mx-Cre)Kyo
Strain Nomenclature C57BL/6-Tg(Mx-Cre)Kyo
Common name/Synonyms Mx-Cre Tg
Strain types mutant
Background strain
Institution Department of Animal Development and Physiology, Kyoto University
Developer
Depositor Kazuhiro Sakamaki
Conditions of distribution It's necessary to obtain developer's consent form on use of biological resources. contact us
Animal Health Report
Strain description

Mx-Cre Tg mice are transgenic mice expressing Cre recombinase under the control of mouse Mx1 promoter. Mx1 is a interferon-induced GTP-binding protein. This strain is used to generate inducible conditional knockout mice.

Reference(s)
  1. Kühn R, Schwenk F, Aguet M, and Rajewsky K. (1995) Inducible gene targeting in mice. Science 269(5229):1427-9. [PMID:7660125]
Resource information
Cryopreserved sperm In-house Genotype
Medium
From other institutions Genotype
Medium
Cryopreserved embryo In-house Mating System
Genotype
Medium
From other institutions Mating System
Genotype
Method
Strain status / Availability Cryopreserved sperm Within 1 month
Cryopreserved embryo Within 1 month
Live animals Approx. 2 months
Gene information
Mutation types transgenic
Gene symbol Mx1, Cre
Gene name [myxovirus (influenza virus) resistance 1, interferon-inducible protein p78 (mouse)], Cre recombinase
Genotyping information Genotyping protocol for C57BL/6-Tg(Mx-Cre)Kyo mice (pdf).